Tetralogy of fallot

This study tests whether a therapeutic education program helps teenagers and young adults with congenital heart disease transition from pediatric to adult medical care. Participants aged 13 to 25 will either receive the education program or standard follow-up. Researchers will me…

This study tested whether giving the steroid methylprednisolone before and during heart surgery could reduce dangerous inflammation in infants under one year old. Over 1,200 babies were randomly assigned to receive either the steroid or a placebo (salt water). Researchers tracked…

This study looked at the SAPIEN XT heart valve, which is placed through a thin tube (catheter) to fix a failed valve in the heart's right ventricle. Researchers wanted to confirm it is safe and works well. They enrolled 57 people with a narrowed or leaky heart valve conduit. The …

This study tested whether giving vitamin E (alpha-tocopherol) during heart surgery could reduce heart muscle damage in children with Tetralogy of Fallot, a birth defect. 58 children aged 1-10 years received either vitamin E or a placebo at the start of surgery. The main goal was …

This study tested a new valve called the Pulsta® Transcatheter Pulmonary Valve in 15 people with congenital heart disease and a faulty pulmonary valve. The valve is implanted through a catheter, avoiding open-heart surgery. Researchers checked if the valve improved blood flow and…

This study is testing whether an artificial intelligence system can accurately identify congenital heart disease in children by analyzing heart sounds. It will involve thousands of children, with and without heart conditions, to compare the AI's performance against traditional me…

This completed study looked at 313 children to see if blood tests and advanced heart scans could help detect congenital heart disease earlier and predict which children might need surgery. Researchers compared children with heart defects to healthy controls using blood biomarkers…

This trial compares two simple educational tools—an animated video and a brochure—against routine care to see which best lowers anxiety and fear in children aged 7 to 10 who need an echocardiogram. All participants have a congenital heart condition and are scheduled for a follow-…

This trial investigates whether using a bedside ultrasound machine can help doctors and nurses place feeding tubes more accurately in children aged 0 to 6 years who have congenital heart disease. The study will compare the accuracy of tube placement when ultrasound is used versus…

This study tested whether using virtual reality glasses during physical therapy can reduce pain, improve blood oxygen levels, and help children walk farther after open heart surgery. Forty children aged 6 to 12 took part. One group used VR glasses during their cardiac rehab exerc…

This study looked at whether different types of exercise training can help adults with congenital heart disease exercise more easily. 47 participants were split into three groups: interval training, moderate continuous training, or usual care (no training). The main goal was to s…

This study tested a special nerve block (serratus anterior plane block) to see if it could reduce pain and the need for strong painkillers like fentanyl in children after heart surgery. 48 children having heart surgery through a chest incision took part. The goal was to find a sa…

This study tested if combining cartoon-watching with nurse interaction could ease pain in children after heart surgery. 70 kids aged 3-7 took part; half got standard pain care, and the other half also watched cartoons with a nurse. The goal was to see if this fun, non-drug approa…

Children with congenital heart disease often need a breathing machine after surgery, and the pressure it creates can affect blood flow to the brain. This study compares conventional ventilation with NAVA, a mode that works with the child's own breathing signals, in 30 children re…

This study looks at whether children born with heart defects who need surgery might also have delays in speech and thinking. Researchers will check the children's cognitive and language skills before their operation and again one and two years after. The goal is to see if speech …

This study tested whether a newer type of MRI called 4D flow can more accurately measure leakage in the pulmonary valve and heart chamber size in people born with tetralogy of Fallot who had corrective surgery. Researchers compared 4D flow MRI with standard 2D MRI in 21 patients …

This study looked at new ways to test blood clotting in 200 children with congenital heart disease undergoing surgery. The goal was to see if newer technologies like TEG, ROTEM, and T2MR could help doctors manage bleeding more precisely and reduce the need for blood transfusions.…

This study looked at 11 people with a repaired heart condition called tetralogy of Fallot who needed a new pulmonary valve. Researchers used MRI scans to measure heart muscle stiffness (fibrosis) and how well the heart pumped during rest and exercise. The goal was to see if these…

This study looked at how well a procedure called catheter ablation works for treating fast heart rhythms in people with congenital heart disease. Researchers treated 40 patients and followed them for one year to see if the abnormal heart rhythm came back. The goal was to understa…

This study tested whether using a contrast dye during 3D ultrasound can accurately measure the size and function of the right heart chamber in people who had surgery for congenital heart disease. 25 participants received an injection of Lumason (an ultrasound contrast agent) and …

This study looked at children aged 6 to 18 who had heart surgery before they were 3 months old. Researchers asked parents to fill out a questionnaire about their child's emotions, behavior, and social skills. The goal was to see if these children face any developmental challenges…

This study looked at 38 infants under 1 year old with congenital heart disease who needed heart surgery. The goal was to understand why some babies get brain injuries during surgery and to gather data for developing better monitoring tools. Researchers used MRI scans and blood sa…

This study tested whether a special belt that creates images of the lungs (Electrical Impedance Tomography) can safely help doctors choose the best pressure settings on a breathing machine for infants under 3 years old. The study included 14 children with various serious conditio…

This study measured how often teenagers develop chronic kidney disease after having heart surgery as young children. Researchers collected blood and urine samples from 120 teens aged 10 to 15 during their regular heart check-ups. The goal was to find out how common kidney damage …

This study tested whether 3D-printed heart models or augmented reality (AR) help first-year medical students understand two rare heart defects better than traditional slide lectures. 26 students took a quiz before and after learning with one of the three methods. The goal was to …

This study looked at 60 children having heart surgery with a bypass machine. It compared two types of filters—hemofilters and hemodialyzers—to see which one better removes inflammatory substances called cytokines. The goal was to find out if the cheaper hemodialyzer could be a sa…