Suppurative periapical periodontitis
MONDO:0006989Localized collection of pus in the tissues that enclose the root of a tooth.
Also known as: dentoalveolar abscess, periapical dental abscess
34 clinical trials for this condition and its sub-types, 12 tagged with Suppurative periapical periodontitis itself.
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Antibiotics after tooth extraction: helpful or unnecessary?
Disease control CompletedThis trial looks at whether antibiotics are needed after removing a tooth with a periapical abscess (an infection at the root tip). Half of the 176 adult participants receive amoxicillin for 5 days after extraction, while the other half get only pain relievers. A dentist checks t…
Sponsor: Subbaiah Institute of Dental Sciences • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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New dental filler shows promise in retreating infected root canals
Disease control CompletedThis study looked at how well a special dental material (calcium silicate sealer) works when re-treating root canals that have failed. 136 adults aged 18-65 with infected teeth were included. The main goal was to see if the infection healed on 3D X-rays and if symptoms like pain …
Sponsor: Ministry of Health, Kuwait • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Scientists track germs in root canals during standard dental care
Knowledge-focused CompletedThis study looked at how the types of bacteria in an infected root canal change during routine dental treatment. Twenty-four adults with a chronic tooth abscess received standard root canal therapy using one of two bleach solutions (5.25% or 3% sodium hypochlorite) followed by a …
Sponsor: Hasanuddin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Laser vs ultrasound: which cleans root canals better?
Knowledge-focused CompletedThis small study tested two methods for cleaning infected root canals: ultrasonic activation and a 980-nm diode laser. Sixteen adults with dead (necrotic) teeth had their root canals cleaned with one of these methods. Researchers checked for leftover bacterial DNA to see which me…
Sponsor: Hasanuddin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC