Laser vs ultrasound: which cleans root canals better?
NCT ID NCT07607028
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small study tested two methods for cleaning infected root canals: ultrasonic activation and a 980-nm diode laser. Sixteen adults with dead (necrotic) teeth had their root canals cleaned with one of these methods. Researchers checked for leftover bacterial DNA to see which method worked better. The goal is to find the most effective way to reduce bacteria during root canal treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 3% sodium hypochlorite irrigation activated by ultrasonic or diode laser
- What this could lead to
- If one method proves better at removing bacteria, it could improve root canal success rates.
- What could go wrong
- This is a very small pilot study with only 16 participants, so results may not apply to all cases. It measures bacterial DNA, not actual infection outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16 people
The number who actually took part.
- Started
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Oct 2025
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older * Patients requiring endodontic treatment for mature single-rooted teeth diagnosed with pulp necrosis * Physically and mentally able to undergo treatment * No use of analgesics or antibiotics within one week before treatment * Teeth without clinical or radiographic evidence of apical periodontitis * Diagnosis confirmed by clinical examination, pulp vitality testing, and periapical radiography Exclusion Criteria: * Teeth with mobility * Periodontal pockets greater than 4 mm * Root fracture or fracture during treatment * Internal or external root resorption * Canal calcification or canal obliteration * Patients with systemic conditions requiring antibiotic prophylaxis for routine dental treatment * Recent antimicrobial exposure that could influence microbial findings
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dental and Oral Hospital Hasanuddin University
Makassar, South Sulawesi, 90245, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a gentler root canal save more tooth and still heal infection?
- Can a different rinse cut pain after root treatment in kids?