Stutter disorder

This early study tests a small, wireless brain implant designed to help people with severe speech problems communicate by thought. Four adults with conditions like locked-in syndrome or ALS will get the implant and learn to control it. The main goal is to see if the device is saf…

This study tests whether low-intensity focused ultrasound (LIFU), a gentle sound wave technique, can safely improve speech fluency in people who stutter. Twenty adults who stutter will receive LIFU or a sham treatment, and researchers will measure changes in stuttering severity a…

This study tests whether a gentle brain stimulation technique (tDCS) combined with standard speech therapy can reduce stuttering severity and its negative impact on daily life. Sixteen adults who stutter will receive both treatments, and researchers will measure changes in speech…

This trial tests a structured, 8-session program designed to help adults who stutter feel less anxious and more confident in job interviews. The program uses techniques like cognitive restructuring, voluntary stuttering, and simulated interviews to gradually reduce fear of negati…

This pilot study tests whether repeated transcranial magnetic stimulation (rTMS) can reduce stuttering in adults. Two participants will receive 10 rTMS sessions, and researchers will measure changes in brain activity and speech. The goal is to see if this non-invasive treatment c…

This phase 2 trial is testing whether the drug lumateperone can reduce stuttering symptoms in adults with moderate to severe childhood-onset stuttering. Participants take either lumateperone (21 mg or 42 mg) or a placebo daily for several weeks. Researchers will measure changes i…

This study compares word learning in late-talking toddlers (ages 2–3) who receive a behavioral treatment called VAULT. One group is taught words from categories they already know (like animals), while the other group learns words from less familiar categories. The goal is to see …

This study tests whether virtual reality (VR) games can make speech therapy more fun and improve how often people practice. Researchers will enroll 30 adults with voice disorders at the Glenrose Rehabilitation Hospital. Participants will use VR speech therapy games at home and in…

This study tests whether a safe, noninvasive brain stimulation technique called HD-tDCS can reduce stuttering symptoms like repetitions and blocks. Fifty adults who stutter will receive a single session of stimulation and complete speaking tasks before and after. The goal is to s…

This study tests whether a gentle, noninvasive electrical current applied to the scalp can improve speech fluency in adults who stutter. Researchers will give 80 participants three sessions of brain stimulation while they read aloud, then measure changes in brain activity and stu…

This study looks at how children who stutter process speech sounds compared to children who do not stutter. Researchers will use hearing tests, brain wave recordings (EEG), and brain scans (fMRI) to measure brain activity. The goal is to understand the differences in speech proce…

This study gives aripiprazole, a drug that affects dopamine, to 40 adults who stutter to see how it changes brain activity during speech. Researchers use brain scans and audio recordings to measure how the brain processes sound before and during speaking. The goal is to better un…

This study collects medical information and samples from people with hearing, balance, taste, smell, voice, speech, or language disorders. Researchers aim to use this data for future studies and to find candidates for other research. Participants receive standard care, and no exp…

This study looks at how the brain uses feedback to control speech in 90 adults aged 18-50, including people who stutter, have dyslexia, and those with typical speech. Participants will do speech tasks, have an MRI scan, and receive mild brain stimulation to see how different brai…

This study uses brain scans (fMRI) to compare brain activity when adults who stutter produce stuttered versus non-stuttered speech. Researchers aim to understand which brain circuits are involved. Fifty adults aged 18-65 who stutter will participate. This is not a treatment study…

This study follows 120 children aged 3-6 who stutter or have typical speech, to learn why some recover naturally. Kids complete speech tests, wear brain-monitoring caps, and speak in virtual reality classrooms. Researchers track brain activity, heart rate, and skin responses to f…

This study looks at how children who stutter perform on rhythm tasks compared to children who don't stutter. Researchers will test rhythm perception and production once a year for three years in 500 children. The goal is to understand how rhythm skills might be linked to brain ac…