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Scientists probe Brain's speech secrets in stuttering and dyslexia

NCT ID NCT07459803

Knowledge-focused Sponsor: Boston University Charles River Campus Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study looks at how the brain uses feedback to control speech in 90 adults aged 18-50, including people who stutter, have dyslexia, and those with typical speech. Participants will do speech tasks, have an MRI scan, and receive mild brain stimulation to see how different brain areas affect speech. The goal is to understand why speech skills vary and how brain differences relate to conditions like stuttering and dyslexia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Mar 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Native speakers of American English * Adults age 18-50 * Age-appropriate cognitive and receptive vocabulary skills * Age-appropriate hearing * Adults with dyslexia will have a history of dyslexia or report of ongoing reading difficulties that will be confirmed at the first screening visit * Adults who stutter will have a history of stuttering that will be confirmed at the first screening visit Exclusion Criteria: * History of neurological disorder, including a history of seizures * Major brain injury, brain surgery, or stroke * Orthodontia or atypical oral structure (e.g., cleft palate) that interferes with speech * Fluency disorder (except those in the persons who stutter cohort), apraxia of speech, or dysarthria * Language or reading disorder (except those in persons with dyslexia cohort) * Standardized score below 80 on the Kaufman Brief Intelligence Test * Standardized score below 1 standard deviation on the NIH Toolbox Picture Vocabulary Test * Pregnancy * Severe claustrophobia * Presence of magnetically or mechanically active implant, or other ferromagnetic material embedded in any part of the body * Significant scalp lesions that would prevent transcranial direct stimulation

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Conditions

The condition(s) this trial relates to.

dyslexia speech disorder stutter disorder Stuttering

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dyslexia Healthy participants Stuttering, developmental

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Boston University

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Boston University Charles River Campus

    RECRUITING

    Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.