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Brain scans reveal how stuttering kids process speech differently

NCT ID NCT05668923

Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Sep 02, 2026 · Updated 2 times

Summary

This study looks at how children who stutter process speech sounds compared to children who do not stutter. Researchers will use hearing tests, brain wave recordings (EEG), and brain scans (fMRI) to measure brain activity. The goal is to understand the differences in speech processing, which may help develop better treatments in the future. The study involves 600 children aged 6-18 who speak English as their primary language.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could reveal how the brain processes speech differently in children who stutter, potentially guiding future therapies.
What could go wrong
This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all children who stutter.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 600 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

5 to 17 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Speaks English as primary language * Language abilities within the typical range * Cognitive abilities within the typical range * No contraindications for MRI Inclusion criteria for children who stutter: * Presence of developmental stuttering (onset in childhood) * No history of other communication disorder Inclusion criteria for children who do not stutter: * No family history of stuttering * No history of other communication disorders (e.g., hearing impairment, language impairment, cognitive impairment/injury) Exclusion Criteria: * Taking medication that alters neural function * Cognitive skills below the typical range * Major medical illness * Not a fluent speaker of English * Pregnant or possibly pregnant * Metal implants in your body (including pacemakers, neurostimulators, or other metal objects) * Shrapnel injuries * Ocular foreign bodies (e.g., metal shavings) * Metal piercings that cannot be removed for the scan * Tattoos containing iron or metal pigments * Prone to claustrophobia * For fMRI, those with head circumference greater than 60cm or whose weight is more than 300 pounds will be excluded due to the size of the fMRI magnet bore

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Conditions

The condition(s) this trial relates to.

stutter disorder Stuttering

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stuttering, childhood

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Michigan

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48105, United States

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

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