Strabismus
MONDO:0003432Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected.
Also known as: squint, strabismus
46 clinical trials for this condition and its sub-types, 28 tagged with Strabismus itself.
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Sub-types of Strabismus
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Exotropia 9 trials · 19 incl. sub-types
2 sub-types
- Alternating exotropia 11 trials
- Monocular exotropia 0 trials
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Intermittent squint 14 trials
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Esotropia 8 trials
3 sub-types
- Accommodative esotropia 1 trial
- Alternating esotropia 1 trial
- Monocular esotropia 0 trials
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Internuclear ophthalmoplegia 3 trials
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Conjugate gaze palsy 1 trial
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Mechanical strabismus 0 trials · 1 incl. sub-types
1 sub-type
- Brown syndrome 1 trial
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Cyclotropia 0 trials
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Hypertropia 0 trials
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Hypotropia 0 trials
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Monofixation syndrome 0 trials
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Paralytic strabismus 0 trials
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Can 3D movies on a handheld game system help straighten Kids' eyes?
Disease control OngoingThis trial tests whether watching specially designed 3D movies on a Nintendo 3DS for four weeks can improve eye alignment in children with intermittent exotropia, a condition where one eye occasionally drifts outward. The study includes children with moderate misalignment and aim…
Sponsor: Retina Foundation of the Southwest • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Timing tylenol: could a fixed schedule beat 'as needed' for kids' post-surgery pain?
Symptom relief PausedThis Phase 2 trial tests whether giving children acetaminophen (Tylenol) on a strict schedule every 6 hours for 48 hours after strabismus surgery reduces pain more than the usual as-needed approach. About 80 children aged 4–12 will take part, with parents and children reporting p…
Phase 2 • Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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Gene hunt: can DNA predict best time for baby eye surgery?
Knowledge-focused OngoingThis study follows 300 children with congenital esotropia (crossed eyes from birth) who had corrective surgery. Researchers will analyze their genes and medical images to see how genetics and the timing of surgery affect eye alignment and the development of 3D vision. The goal is…
Sponsor: Qiyu Bo • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC