Gene hunt: can DNA predict best time for baby eye surgery?
NCT ID NCT06614335
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 300 children with congenital esotropia (crossed eyes from birth) who had corrective surgery. Researchers will analyze their genes and medical images to see how genetics and the timing of surgery affect eye alignment and the development of 3D vision. The goal is to find personalized treatment strategies to improve outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors personalize surgery timing for children with congenital esotropia, potentially improving long-term eye alignment and depth perception.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not apply to all children, and genetic findings may not lead to immediate clinical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Mar 2024
- Expected to finish
-
Mar 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Children 0-3 years of age undergoing surgery for congenital esotropia.
- Ages
-
Up to 3 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children diagnosed with congenital esotropia and treated with surgery, regardless of gender; * Children aged 0-36 months; * The guardian of the patient voluntarily signs the informed consent. Exclusion Criteria: * Esotropia found within 6 months of age due to anatomical abnormalities, extraocular muscle fibrosis, or paralysis or absence of nerves innervating the extraocular muscle; * There are diseases or structural abnormalities affecting ocular vision development, such as congenital cataract, congenital microeyeball, congenital glaucoma, genetic or blinding eye diseases with clear genetic mutations, such as Lerber amaurosis and ocular albinism; * Those deemed unsuitable for inclusion by the researchers.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Congenital esotropia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shanghai
Shanghai, China