Stomatitis

This study tests whether a special mouthwash containing N-acetylcysteine can prevent painful mouth sores (oral mucositis) in patients receiving a stem cell transplant. These sores are a common and serious side effect that can cause severe pain and longer hospital stays. The trial…

This study tests if shining a special light inside the mouth, outside the cheek, or both can prevent severe mouth sores in people getting a stem cell transplant. About 78 patients will receive daily light therapy during their transplant stay. The goal is to find the best way to r…

Researchers are testing a new medical device called Bocaliner in people who have painful mouth sores caused by chemotherapy or radiation. The device is held in the mouth after using medicated mouthwashes, gels, or rinses, with the goal of keeping those treatments in contact with …

This phase 2 trial tests whether the drug RRx-001 can prevent severe oral mucositis (painful mouth sores) in 216 patients with head and neck cancer receiving standard chemoradiation. Patients are randomly assigned to receive RRx-001 or a placebo alongside their usual treatment. T…

This early-phase study tests whether a mouthwash made from copaiba, a natural oil from the Amazon, can safely help prevent and treat painful mouth sores caused by radiation therapy in 20 adults with head and neck cancer. Researchers will find the highest safe dose and measure pai…

This study planned to test a mouthwash made from copaíba oil, a natural resin, to prevent and treat painful mouth sores (oral mucositis) in people with oral cancer undergoing radiation. The trial was set to include 40 patients, half using the copaíba mouthwash and half a placebo,…

This real-world study follows 33,000 cancer patients in France using the CareMin650™ device, which shines light on mouth sores and skin burns caused by chemotherapy or radiation. The goal is to see if this light therapy reduces the severity of these painful side effects. Research…

This study tests whether the antiviral drug valacyclovir can prevent or reduce painful mouth sores (oral mucositis) in adults receiving radiotherapy for head and neck cancer. Researchers will give either valacyclovir or a placebo to 84 participants during their radiation treatmen…

This study looks at whether a hands-on, simulation-based training program helps people with a new stoma feel more confident and capable in caring for it. About 70 adults who have a stoma for the first time will either receive standard education or the simulation-based training. R…

This study looks at whether a special home care program helps people with a new stoma (a surgical opening on the belly) recover better after colorectal cancer surgery. About 98 adults who had a stoma created will get extra support and teaching to manage their stoma at home. The g…

This study looks at whether using augmented reality (AR) can improve how nurses learn to care for oral mucositis, a painful mouth condition caused by cancer treatments. About 110 nurses from a hospital in Taiwan will take part. Researchers will measure their knowledge, skills, an…