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Skin pigmentation disorder
MONDO:0019288A pigmentation disease that involves the zone of skin.
Also known as: pigmentation anomaly of the skin, pigmentation disease of zone of skin, zone of skin pigmentation disease, pigmentation disease
63 clinical trials for this condition and its sub-types, 12 tagged with Skin pigmentation disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Skin pigmentation disorder
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Hyperpigmentation of the skin 17 trials · 31 incl. sub-types
24 sub-types
- Legius syndrome 5 trials
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Schwannomatosis 3 trials Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Dyschromatosis universalis hereditaria 1 trial Sub-types →
- H syndrome 0 trials
- Naegeli-Franceschetti-Jadassohn syndrome 0 trials
- Acromelanosis 0 trials
- Cafe au lait spots, multiple 0 trials
- Dermatopathia pigmentosa reticularis 0 trials
- Extrasystoles-short stature-hyperpigmentation-microcephaly syndrome 0 trials
- Familial generalized lentiginosis 0 trials
- Familial progressive hyperpigmentation 0 trials Sub-types →
- Gastrocutaneous syndrome 0 trials
- Hyperkeratosis-hyperpigmentation syndrome 0 trials
- Hyperpigmentation, progressive cribriform and zosteriform 0 trials
- Leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome 0 trials
- Linear and whorled nevoid hypermelanosis 0 trials
- Mosaic Legius syndrome 0 trials
- Nail and teeth abnormalities-marginal palmoplantar keratoderma-oral hyperpigmentation syndrome 0 trials
- Osteopathia striata-pigmentary dermopathy-white forelock syndrome 0 trials
- Phakomatosis pigmentovascularis 0 trials Sub-types →
- Reticulate acropigmentation of Kitamura 0 trials
- Severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome 0 trials
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Hypopigmentation of the skin 2 trials · 21 incl. sub-types
10 sub-types
- Syndromic oculocutaneous albinism 0 trials · 12 incl. sub-types Sub-types →
- Oculocutaneous albinism 4 trials Sub-types →
- Piebaldism 4 trials
- Tietz syndrome 1 trial
- Ito hypomelanosis 0 trials
- Albinism-hearing loss syndrome 0 trials
- Deaf blind hypopigmentation syndrome, Yemenite type 0 trials
- Deafness, congenital, with total albinism 0 trials
- Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies 0 trials
- Piebald trait-neurologic defects syndrome 0 trials
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Reticulate pigment disorder 0 trials · 5 incl. sub-types
3 sub-types
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Reticulate acropigmentation of Kitamura 0 trials
Most studied deeper sub-types
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Can a Drug-Radiation combo outsmart Treatment-Resistant colorectal cancer?
Disease control CancelledThis phase 2 trial is testing whether combining an experimental drug called S-531011 with a precise radiation technique known as RadScopal can help control metastatic colorectal cancer that has not responded to prior treatments. The study enrolls about 30 adults with advanced dis…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Stem cell transplant offers new hope for kids with rare immune diseases
Disease control OngoingThis study tests a donor stem cell transplant for people with severe immune system problems, like SCID and Wiskott-Aldrich syndrome. The goal is to help the body make healthy blood cells and fight infections. Participants receive donated stem cells to rebuild their immune system.…
Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New drug shows promise for controlling rare kidney disorders
Disease control OngoingThis study tests the long-term safety and effectiveness of pegcetacoplan in 100 people with two rare kidney diseases, C3 glomerulopathy and IC-MPGN. Participants previously completed a one-year trial and saw benefit from the drug. The goal is to see if pegcetacoplan can keep redu…
Phase 3 • Sponsor: Apellis Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Milder stem cell transplant shows promise for kids with immune disorders
Disease control OngoingThis study tests a stem cell transplant using a milder chemotherapy-like regimen to treat children and young adults (up to age 28) with various immune system disorders. The goal is to help the donor stem cells settle in the body with fewer side effects. The study involves 20 part…
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New hope for rare kidney disease patients: early access to pegcetacoplan
Disease control ApprovedThis program provides early access to pegcetacoplan for people aged 12 and older with C3 glomerulopathy or primary IC-MPGN, rare kidney diseases that can lead to kidney failure. Participants must have active disease with significant protein in their urine. The goal is to offer a …
Sponsor: Apellis Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Newborn screening study aims to catch rare diseases at birth
Diagnosis OngoingThis study offers voluntary screening for newborns in North Carolina to detect a wide range of rare health conditions early. Using a small blood sample already collected at birth, the program tests for dozens of disorders, including spinal muscular atrophy, cystic fibrosis, and m…
Sponsor: RTI International • Aim: Diagnosis
Last updated Jul 03, 2026 00:00 UTC
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New study tests gentler tooth removal for faster implant healing
Symptom relief OngoingThis study compares two tools, piezotome and periotome, used for gentle tooth extraction before placing a dental implant right away in the front upper teeth. The goal is to see which tool better preserves bone and gum tissue, leading to improved healing and appearance. Thirty adu…
Sponsor: Alexandria University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Scientists dig into tissue samples to unravel lung scarring mystery
Knowledge-focused OngoingThis study collects and analyzes blood, DNA, and tissue samples from 315 adults with pulmonary fibrosis, their relatives, and healthy volunteers. The goal is to learn more about the disease's causes, not to test a new treatment. Researchers hope the findings will guide future the…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Which Mini-Implant size works best? new study aims to find out
Knowledge-focused OngoingThis study tests two different diameters (1.6mm and 2mm) of mini-implants placed in the upper jaw to support orthodontic tooth movement. Twenty people receiving braces will get one size on each side of their mouth. Researchers will measure how stable the implants are, how much pa…
Sponsor: University of Baghdad • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Study reveals pulse oximeters may overestimate oxygen in Darker-Skinned newborns
Knowledge-focused OngoingThis study looks at whether pulse oximeters, which measure oxygen levels, give less accurate readings for newborns with darker skin. Researchers will compare oxygen readings from the device with actual blood oxygen levels in 163 babies of different skin tones. The goal is to find…
Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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10,000 people to have eye and skin pigments measured in nutrition study
Knowledge-focused By invitation onlyThis study aims to understand how diet affects the eyes and skin by measuring natural pigments called carotenoids. Researchers will use non-invasive methods to check levels in the eye and skin, and also test blood in some participants. Anyone age 7 or older having a routine eye e…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC