Skin pigmentation disorder
MONDO:0019288A pigmentation disease that involves the zone of skin.
Also known as: pigmentation anomaly of the skin, pigmentation disease of zone of skin, zone of skin pigmentation disease, pigmentation disease
63 clinical trials for this condition and its sub-types, 12 tagged with Skin pigmentation disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Skin pigmentation disorder
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Hyperpigmentation of the skin 17 trials · 31 incl. sub-types
24 sub-types
- Legius syndrome 5 trials
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Schwannomatosis 3 trials Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Dyschromatosis universalis hereditaria 1 trial Sub-types →
- H syndrome 0 trials
- Naegeli-Franceschetti-Jadassohn syndrome 0 trials
- Acromelanosis 0 trials
- Cafe au lait spots, multiple 0 trials
- Dermatopathia pigmentosa reticularis 0 trials
- Extrasystoles-short stature-hyperpigmentation-microcephaly syndrome 0 trials
- Familial generalized lentiginosis 0 trials
- Familial progressive hyperpigmentation 0 trials Sub-types →
- Gastrocutaneous syndrome 0 trials
- Hyperkeratosis-hyperpigmentation syndrome 0 trials
- Hyperpigmentation, progressive cribriform and zosteriform 0 trials
- Leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome 0 trials
- Linear and whorled nevoid hypermelanosis 0 trials
- Mosaic Legius syndrome 0 trials
- Nail and teeth abnormalities-marginal palmoplantar keratoderma-oral hyperpigmentation syndrome 0 trials
- Osteopathia striata-pigmentary dermopathy-white forelock syndrome 0 trials
- Phakomatosis pigmentovascularis 0 trials Sub-types →
- Reticulate acropigmentation of Kitamura 0 trials
- Severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome 0 trials
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Hypopigmentation of the skin 2 trials · 21 incl. sub-types
10 sub-types
- Syndromic oculocutaneous albinism 0 trials · 12 incl. sub-types Sub-types →
- Oculocutaneous albinism 4 trials Sub-types →
- Piebaldism 4 trials
- Tietz syndrome 1 trial
- Ito hypomelanosis 0 trials
- Albinism-hearing loss syndrome 0 trials
- Deaf blind hypopigmentation syndrome, Yemenite type 0 trials
- Deafness, congenital, with total albinism 0 trials
- Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies 0 trials
- Piebald trait-neurologic defects syndrome 0 trials
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Reticulate pigment disorder 0 trials · 5 incl. sub-types
3 sub-types
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Reticulate acropigmentation of Kitamura 0 trials
Most studied deeper sub-types
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Warming hands may sharpen oxygen readings in ICU patients
Disease control Not yet recruitingPulse oximeters, which clip onto a finger to estimate blood oxygen levels, can be less accurate when blood flow to the fingers is poor, a common issue in critically ill patients. This trial tests whether warming the hand and lower forearm for 15 minutes improves the accuracy of t…
Sponsor: Vastra Gotaland Region • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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Robot-Assisted surgery showdown: which fix works best for rare bowel disease?
Disease control Not yet recruitingThis study compares two surgical techniques—Duhamel and Soave—for treating total colonic Hirschsprung disease, a severe birth defect where nerve cells are missing from the colon. Fifty children who had a first surgery as newborns will receive one of the two procedures. Researcher…
Sponsor: Zunyi Medical College • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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A 5-Day genetic test could slash time to transplant for children with rare immune disease
Diagnosis Not yet recruitingThis trial tests whether a new ultra-rapid genetic test, using third-generation sequencing, can diagnose familial lymphohistiocytosis (FHL) in children within 5 days instead of the usual 6-8 weeks. FHL is a rare, life-threatening genetic condition where the immune system attacks …
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Diagnosis
Last updated Aug 05, 2026 00:00 UTC
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Can a common antipsychotic keep cannabis users out of the ER?
Symptom relief Not yet recruitingThis trial tests whether giving patients a prescription for haloperidol to use as needed at home can help control symptoms of cannabinoid hyperemesis syndrome — a condition marked by severe nausea, vomiting, and abdominal pain from heavy cannabis use. The goal is to see if having…
Early phase 1 • Sponsor: University of Illinois at Chicago • Aim: Symptom relief
Last updated Sep 03, 2026 00:00 UTC
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Can seaweed microspicules turn back the clock on aging skin?
Symptom relief Not yet recruitingThis pilot trial tests a topical cream containing patented microspicules that deliver Penghu seaweed extracts to the skin. The study will enroll healthy adults aged 40-65 with signs of facial aging or pigmentation, applying the cream to one side of the face for comparison. Resear…
Sponsor: Chung Shan Medical University • Aim: Symptom relief
Last updated Aug 21, 2026 00:00 UTC
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New Serum-Peel combo aims to fade dark spots and wrinkles
Symptom relief Not yet recruitingThis study tests whether adding MELA B3 serum to a 35% glycolic acid peel works better than the peel alone for treating dark spots (melasma, post-acne marks, age spots) and signs of aging. About 80 adults aged 30-70 in Buenos Aires will use the treatments for 3 months. The goal i…
Sponsor: Cosmetique Active International • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Saffron supplement tested for Wrinkle-Fighting powers
Symptom relief Not yet recruitingThis study tests whether taking a daily saffron extract capsule can improve skin health by reducing wrinkles, fine lines, and dark spots. Fifty healthy adults aged 30 to 55 will take either the saffron supplement or a placebo for a set period. Researchers will use special skin sc…
Sponsor: NovoBliss Research Pvt Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Could you help scientists unlock genetic cancer secrets?
Knowledge-focused Not yet recruitingThis study screens up to 1,000 people with personal or family histories of certain cancers to see if they qualify for ongoing genetics research at the National Cancer Institute. Participants fill out a 15-20 minute online survey about their health and family history. No treatment…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 20, 2026 00:00 UTC