Saffron supplement tested for Wrinkle-Fighting powers
NCT ID NCT07324759
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking a daily saffron extract capsule can improve skin health by reducing wrinkles, fine lines, and dark spots. Fifty healthy adults aged 30 to 55 will take either the saffron supplement or a placebo for a set period. Researchers will use special skin scanners to measure changes in texture, tone, and firmness.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- saffron extract (10 mg capsule)
- What this could lead to
- If it works, this could point toward a natural supplement for reducing wrinkles and age spots.
- What could go wrong
- This is a small, early exploratory study with only 50 participants. Results may not apply to everyone, and any benefits might be minor or not noticeable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: 30 to 55 years (both inclusive) at the time of consent. 2. Sex: Adult male and female having wrinkles and fine lines at crow feet's area, facial hyperpigmentation and dark spots such as tan, pimple marks, sunspots, age spots, uneven skin tone on both side of face. 3. Females of childbearing potential should have a self-reported negative urine pregnancy test at the time of screening visit. 4. Subjects should not have used any cosmetic, nutraceutical or therapeutic products for skin ageing in last 1 month. 5. Subjects must be willing to stop using any cosmetics or any medical products for skin ageing for the duration of the study. 6. Subjects are not allowed to participate in any other study until this study is complete. 7. Subjects must be willing and able to follow the study directions and to return for all specified visits with the product. 8. Subjects must agree to record each use of the test products in the subject's diary card on daily basis. 9. Subjects must agree to record medication use during the study. Exclusion Criteria: 1. Subjects who are on steroids for last six months and using immunosuppressive, anti-inflammatory, or hormone-modulating medications that may interfere with study outcomes. 2. Subjects who have used any cosmetic, nutraceutical or therapeutic products for skin last one months. 3. Subjects currently using any oral supplement and topical products containing kojic acid, glycolic acid, niacinamide, alpha arbutin, vitamin C, retinoids, peptides, exfoliating acids, or any other skin-lightening, anti-ageing, or depigmenting agents within the past 4 weeks. 4. Subjects with a known history of hypersensitivity, allergic reactions, or intolerance (such as drowsiness, stomach discomfort, nausea, or vomiting). 5. Subjects with other dermatologic diseases whose presence or products could interfere with the assessment of study. 6. Subjects that are pregnant and/or breastfeeding. 7. The subject has a known allergy or sensitivity to product ingredients. 8. Subjects if do not agree to limit sun exposure to affected areas such as face during prolonged sun exposure. 9. The subject has any other skin conditions i.e. cuts, scratches, ring worms, etc. which in the opinion of the Investigator, will interfere with the study results or will create undue risk for the subject. 10. The subject has any of the conditions or factors that the Investigator believes may affect the response of the skin or the interpretation of the test results. 11. The subject is currently taking or has taken any medication, which the Investigator believes may influence the interpretation of the data. 12. Any other condition which could warrant exclusion from the study, as per the dermatologist's/investigator's discretion.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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