Severe acute respiratory syndrome
MONDO:0005091A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death.
Also known as: SARS, SARS coronavirus caused disease or disorder, SARS coronavirus disease or disorder, SARS coronavirus infectious disease, acute respiratory coronavirus infection
33 clinical trials for this condition and its sub-types, 30 tagged with Severe acute respiratory syndrome itself.
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Can an old malaria drug help fight severe COVID-19?
Disease control CancelledThis Phase 3 trial tests whether hydroxychloroquine, given alone or with azithromycin, can improve outcomes for adults hospitalized with moderate to severe COVID-19 lung disease. Participants receive hydroxychloroquine for 10 days, and some also get azithromycin for 5 days. Resea…
Phase 3 • Sponsor: Apsen Farmaceutica S.A. • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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Thyroid hormone sprayed into lungs to fight COVID ARDS? trial pulled before start
Disease control CancelledThis study planned to test whether putting a thyroid hormone (T3) directly into the lungs could help people with severe COVID-19 who need a breathing machine. The goal was to reduce fluid in the lungs and shorten time on a ventilator. However, the trial was withdrawn before any p…
Phase 2 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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COVID plasma trial pulled before it even started
Disease control CancelledThis study planned to give blood plasma from recovered COVID-19 patients to people in the ICU with severe COVID-19. The goal was to see if it could help them breathe better and survive. However, the trial was withdrawn before enrolling any participants, so no results are availabl…
Phase 1 • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Rapid COVID test vs. gold standard: study aimed to see if cheap antigen tests work for contact tracing
Diagnosis CancelledThis study planned to compare a rapid antigen detection test against the standard PCR test for diagnosing COVID-19 in people who were close contacts of infected patients but had no symptoms. The goal was to see if the quick, inexpensive antigen test could reliably identify contag…
Sponsor: Juan Fernando Masa Jiménez • Aim: Diagnosis
Last updated Jun 27, 2026 12:25 UTC
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Can a mild case of COVID-19 harm your kidneys? urine tests may hold the answer
Knowledge-focused By invitation onlyThe KIDCOV study investigates whether mild or asymptomatic COVID-19 that does not require hospitalization increases the risk of kidney injury. Researchers enroll 2,000 adults who tested positive or negative for COVID-19, balanced by race and ethnicity across California, Michigan,…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Scientists compare immune responses to viral and bacterial infections in ICU patients
Knowledge-focused OngoingThis study looks at how the immune system of patients in the intensive care unit (ICU) responds to severe infections caused by viruses or bacteria. Researchers will take extra blood samples from 38 adults to analyze immature granulocytes, a type of immune cell. The goal is to see…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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COVID vaccine clot study scrapped before start
Knowledge-focused CancelledThis study aimed to collect medical information from people who developed unusual blood clots within four weeks of receiving a COVID-19 vaccine. The goal was to better understand any possible link between the vaccine and these rare events. However, the study was withdrawn before …
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC