Sarcoidosis

This Phase 3 trial tested a drug called efzofitimod in 268 adults with pulmonary sarcoidosis, a condition that causes lung inflammation. Participants received either the drug or a placebo every 4 weeks for 48 weeks. The main goal was to see if the drug could help people safely re…

This study tested whether H.P. Acthar Gel can improve symptoms and quality of life in people with CNS sarcoidosis, a rare condition where inflammation affects the brain and spinal cord. Four adults with the disease received the gel to see if it could control disease activity and …

This study tested an inhaled medication called treprostinil in 5 people with sarcoidosis who also have lung scarring and high blood pressure in the lungs. The goal was to see if the drug could improve blood flow and heart function. Participants took the drug and were monitored wi…

This study tested whether a special lung MRI can replace CT scans for diagnosing idiopathic pulmonary fibrosis (IPF), a scarring lung disease. Researchers compared MRI to standard CT in 60 patients to see if MRI could spot the same key signs of IPF without using radiation. The go…

This study tested whether adding a tiny forceps biopsy to the standard needle biopsy during a lung ultrasound procedure helps doctors diagnose sarcoidosis more often. Fifty-five adults with enlarged lymph nodes in the chest took part. The goal was to see if the combined approach …

This study tested a device called SUDOSCAN, which measures sweat function in just two minutes, to see if it can detect small fiber nerve damage in people with autoimmune diseases (like lupus or rheumatoid arthritis) or unexplained pain. Researchers enrolled 139 adults and compare…

This study looked at whether a pulmonary rehabilitation program helps people with Stage IV pulmonary sarcoidosis (advanced lung scarring) become more active in their daily lives. 38 adults took part and were followed for one year. The program aimed to improve exercise ability, re…

This study collected blood, saliva, and eye fluid samples from 343 people with uveitis, an inflammatory eye disease that can cause vision loss. Researchers aimed to learn which genes and other factors might lead to the disease and affect treatment response. Participants were foll…

This study looked at over 13,000 people with chronic inflammatory rheumatism or autoimmune diseases who had or were suspected to have COVID-19. Researchers tracked how many developed severe COVID-19 requiring intensive care or leading to death. They also examined risk factors lik…

This study aimed to create and test a new questionnaire called CARD-SARC that measures how cardiac sarcoidosis affects patients' daily lives and well-being. Researchers worked with 130 adults diagnosed with cardiac sarcoidosis at two NHS specialist centres. The goal was to develo…

This study measured two newer blood markers (calprotectin and serum amyloid protein) alongside standard tests in 20 children with juvenile arthritis and related conditions. The goal was to see if these markers could better track disease flare-ups in everyday clinic visits. The st…

This completed study from Alexandria University looked at 40 adults with lung sarcoidosis who were receiving or about to start immunosuppressive therapy. Researchers tracked them for 12 months to see if any developed lymphoma, confirmed by lymph node biopsy. The goal was to under…

This study collected information from 2,200 people with sarcoidosis around the world using online surveys. The goal was to learn more about how the disease affects different people, not just those seen at major medical centers. Participants also had the option to provide a DNA sa…

This study looked at whether the seasonal flu vaccine works as well in people with sarcoidosis as it does in healthy people. Researchers gave the flu shot to 190 adults with sarcoidosis and compared their immune response to a group of healthy volunteers. The goal was to see if th…