Retinal disorder
MONDO:0005283Any disease or disorder of the retina.
Also known as: eye disease of retina, retina eye disease, retinopathy
959 clinical trials for this condition and its sub-types, 89 tagged with Retinal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Retinal disorder
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Retinal degeneration 41 trials · 572 incl. sub-types
6 sub-types
- Inherited retinal dystrophy 41 trials · 510 incl. sub-types Sub-types →
- Macular degeneration 212 trials · 426 incl. sub-types Sub-types →
- Retinoschisis 5 trials · 6 incl. sub-types Sub-types →
- Peripheral retinal degeneration 1 trial · 2 incl. sub-types Sub-types →
- Cone dystrophy 1, X-linked 0 trials
- Cone dystrophy 5, X-linked 0 trials
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Retinal vascular disorder 9 trials · 324 incl. sub-types
12 sub-types
- Diabetic retinopathy 148 trials · 260 incl. sub-types Sub-types →
- Retinal vascular occlusion 0 trials · 53 incl. sub-types Sub-types →
- Exudative vitreoretinopathy 1 trial · 35 incl. sub-types Sub-types →
- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations 3 trials
- Retinal telangiectasia 0 trials · 2 incl. sub-types Sub-types →
- Retinal vasculitis 2 trials
- Retinal hemangioblastoma 1 trial Sub-types →
- Retinal microaneurysm 1 trial
- Arteriosclerotic retinopathy 0 trials
- Familial retinal arterial macroaneurysm 0 trials
- Perifoveal exudative vascular anomalous complex 0 trials
- Vasoproliferative tumor of retina 0 trials
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Inherited vitreoretinopathy 0 trials · 58 incl. sub-types
5 sub-types
- Vitreoretinal degeneration 0 trials · 45 incl. sub-types Sub-types →
- Congenital vitreoretinal dysplasia 0 trials · 9 incl. sub-types Sub-types →
- Vitreous detachment 5 trials
- NDP-related vitreoretinopathy 0 trials Sub-types →
- TSPAN12-related vitreoretinopathy 0 trials Sub-types →
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Retinal detachment 28 trials · 52 incl. sub-types
2 sub-types
- Rhegmatogenous retinal detachment 23 trials Sub-types →
- Retinal perforation 18 trials
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Retina neoplasm 2 trials · 36 incl. sub-types
5 sub-types
- Retinal cancer 2 trials · 35 incl. sub-types Sub-types →
- Retinal cell neoplasm 0 trials · 34 incl. sub-types Sub-types →
- Benign neoplasm of retina 0 trials · 1 incl. sub-types Sub-types →
- Retinal capillary malformation 0 trials
- Retinal neuroblastoma 0 trials
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Retinal edema 1 trial · 28 incl. sub-types
1 sub-type
- Macular retinal edema 19 trials · 27 incl. sub-types Sub-types →
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Macular holes 19 trials
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Night blindness 5 trials · 10 incl. sub-types
3 sub-types
- Congenital stationary night blindness 2 trials · 5 incl. sub-types Sub-types →
- Abnormal threshold of rods 0 trials
- Acquired night blindness 0 trials
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Retinitis 1 trial · 10 incl. sub-types
5 sub-types
- Optic papillitis 5 trials Sub-types →
- Cytomegalovirus retinitis 2 trials
- Retinal vasculitis 2 trials
- Histoplasmosis retinitis 1 trial
- Acute retinal necrosis syndrome 0 trials
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Central serous chorioretinopathy 8 trials
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Proliferative vitreoretinopathy 7 trials
1 sub-type
- CAPN5-related vitreoretinopathy 0 trials
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Achromatopsia 4 trials · 6 incl. sub-types
6 sub-types
- Blue cone monochromacy 2 trials
- Achromatopsia 7 1 trial
- Achromatopsia 2 0 trials
- Achromatopsia 3 0 trials
- Achromatopsia 4 0 trials
- Achromatopsia 6 0 trials
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Retinal ciliopathy 0 trials · 2 incl. sub-types
9 sub-types
- Leber congenital amaurosis 10 2 trials
- Leber congenital amaurosis with early-onset deafness 0 trials
- Cone-rod dystrophy 16 0 trials
- Retinitis pigmentosa 23 0 trials
- Retinitis pigmentosa 51 0 trials
- Retinitis pigmentosa 55 0 trials
- Retinitis pigmentosa 64 0 trials
- Retinitis pigmentosa 74 0 trials
- Retinitis pigmentosa 80 0 trials
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Hypertensive retinopathy 1 trial
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Iris hypoplasia with glaucoma 1 trial
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Retinal ischemia 1 trial
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1 sub-type
- Neuroretinitis 0 trials
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Eales disease 0 trials
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Acute macular neuroretinopathy 0 trials
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Angioid streaks 0 trials
1 sub-type
- Angioid streaks of choroid 0 trials
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Autoimmune retinopathy 0 trials
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Bradyopsia 0 trials
2 sub-types
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Cancer-associated retinopathy 0 trials
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Isolated chorioretinal dystrophy 0 trials
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Isolated foveal hypoplasia 0 trials
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Melanoma associated retinopathy 0 trials
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Myopic macular degeneration 0 trials
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Persistent placoid maculopathy 0 trials
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Rubeosis iridis 0 trials
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Torpedo maculopathy 0 trials
Most studied deeper sub-types
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Gene therapy shot could end frequent eye injections for wet AMD
Disease control OngoingThis early-stage trial tests a one-time gene therapy injection (NG101) for wet age-related macular degeneration. The therapy uses a harmless virus to deliver a gene that makes a drug inside the eye, aiming to reduce the need for repeated anti-VEGF injections. About 20 adults aged…
Phase 1/2 • Sponsor: Elisigen, Inc. • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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One-Shot gene therapy could end monthly eye injections for wet AMD
Disease control OngoingThis study tests a one-time gene therapy called RGX-314 for wet age-related macular degeneration (AMD), a leading cause of vision loss. About 714 adults aged 50-89 who currently need regular eye injections will receive either the gene therapy or standard treatment. The goal is to…
Phase 3 • Sponsor: AbbVie • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New eye injection aims to slow blindness in rare genetic disease
Disease control OngoingThis study tests an experimental drug called ultevursen for people with retinitis pigmentosa caused by a specific gene mutation (USH2A). The drug is injected into the eye and may help slow vision loss. The trial involves 81 participants, some of whom will receive a sham (fake) in…
Phase 2 • Sponsor: Laboratoires Thea • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Experimental eye drug shows promise for rare Blindness-Causing disease
Disease control OngoingThis study tests an experimental drug called VP-001 for people with a rare genetic eye disease that causes vision loss. The drug is injected into the eye and aims to slow or stop further damage. Researchers will check safety and measure any changes in eyesight over about two year…
Phase 1/2 • Sponsor: PYC Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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One-Time eye injection could slow blindness in retinitis pigmentosa
Disease control OngoingThis study tests a gene therapy called SPVN06 for retinitis pigmentosa, an inherited eye disease that causes gradual vision loss. The treatment is given as a single injection under the retina. The trial includes 33 adults with advanced disease and will check safety and whether it…
Phase 1/2 • Sponsor: SparingVision • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Gene therapy could end frequent eye injections for wet AMD
Disease control OngoingThis study tests a one-time gene therapy called RGX-314 for wet age-related macular degeneration (AMD), a leading cause of vision loss. The treatment aims to help the eye produce its own medicine to stop leaky blood vessels, potentially replacing the need for repeated eye injecti…
Phase 2/3 • Sponsor: AbbVie • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Gene therapy for wet AMD: could this mean fewer eye injections?
Disease control OngoingThis study follows 23 people with wet age-related macular degeneration who received a single dose of ADVM-022 gene therapy in an earlier trial. Researchers are checking how safe the treatment is over time and whether it continues to control the disease, potentially reducing the n…
Sponsor: Adverum Biotechnologies, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Stem cells injected into eyes: a new hope for blindness?
Disease control OngoingThis early-stage trial is testing whether it is safe to inject a person's own bone marrow stem cells into their eye to treat vision loss from conditions like macular degeneration and diabetic retinopathy. Fifteen adults with severe vision loss will receive the injection and be mo…
Phase 1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Common heart drug may shield eyes of type 1 diabetes patients
Disease control OngoingThis study tests whether fenofibrate, a drug typically used to lower blood fats, can slow the worsening of diabetic retinopathy (eye damage) in adults with type 1 diabetes. Over 400 participants take either fenofibrate or a placebo daily for three years. The goal is to see if the…
Phase 3 • Sponsor: University of Sydney • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New eye tests could speed up retinitis pigmentosa treatment trials
Knowledge-focused OngoingThis study aims to find better ways to measure how retinitis pigmentosa (a genetic eye disease that causes vision loss) progresses over time. Researchers will use advanced imaging and vision tests in 40 people with specific genetic forms of the disease. The goal is to identify re…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Robot eye scanner study pulled before it started
Knowledge-focused CancelledThis study planned to test a new robotic system that helps take detailed 3D images of the far edges of the retina, an area that is hard to see with standard eye scanners. The goal was to see if the robot could make imaging easier and more comfortable for healthy adults. However, …
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can we predict heart disease in kids? new study seeks answers
Knowledge-focused OngoingThis study looks at over 1,000 South African children ages 5 to 9 to understand why some develop early signs of high blood pressure and heart problems. Researchers will measure blood pressure, body fat, and fitness, and test blood for early warning markers. The goal is to find wa…
Sponsor: North-West University, South Africa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can blood stem cells predict diabetic eye disease?
Knowledge-focused OngoingThis study looks at blood stem cells (called EPCs) in people with and without diabetes to see if they work differently. Researchers want to know if these cells can predict diabetic retinopathy, an eye disease that can cause vision loss. The study involves 78 adults, including 39 …
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Genetic clues to childhood obesity: study seeks answers
Knowledge-focused OngoingThis study looks at the genes of 1000 people with severe early-onset obesity to find rare genetic causes. It focuses on conditions like Bardet-Biedl syndrome. The goal is to better understand these conditions and improve how they are diagnosed. Participants provide a blood or sal…
Sponsor: Rolfs Consulting und Verwaltungs-GmbH (RCV) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Laser after eye surgery may boost recovery, small study hints
Knowledge-focused By invitation onlyThis study follows 100 people having surgery to remove a scar-like membrane on the retina (epiretinal membrane). Half will also receive a gentle laser treatment one month after surgery. Researchers will measure vision and eye structure changes over four months to see if the laser…
Sponsor: Pomeranian Medical University Szczecin • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:39 UTC