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Respiratory tract neoplasm
MONDO:0020641A benign or malignant, primary or metastatic neoplasm involving the respiratory tract.
Also known as: neoplasm of respiratory tract, neoplasm of the respiratory tract, neoplasm, respiratory tract, neoplasms, respiratory tract, respiratory system neoplasm, respiratory tract neoplasm, respiratory tract tumor, respiratory tract tumour
5577 clinical trials for this condition and its sub-types, 32 tagged with Respiratory tract neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Respiratory tract neoplasm
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Lung neoplasm 1,367 trials · 4,039 incl. sub-types
10 sub-types
- Lung cancer 1,207 trials · 3,941 incl. sub-types Sub-types →
- Lung neuroendocrine neoplasm 21 trials · 540 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Lung PEComa 0 trials · 1 incl. sub-types Sub-types →
- Pulmonary sulcus neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
- Fibroma of lung 0 trials
- Hamartoma of lung 0 trials Sub-types →
- Lung germ cell tumor 0 trials
- Lung hilum neoplasm 0 trials Sub-types →
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Nasopharyngeal neoplasm 37 trials · 226 incl. sub-types
3 sub-types
- Malignant tumor of nasopharynx 9 trials · 213 incl. sub-types Sub-types →
- Benign neoplasm of nasopharynx 0 trials
- Nasopharyngeal teratoma 0 trials
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Laryngeal neoplasm 72 trials · 138 incl. sub-types
6 sub-types
- Larynx cancer 41 trials · 125 incl. sub-types Sub-types →
- Glottis neoplasm 3 trials · 12 incl. sub-types Sub-types →
- Supraglottis neoplasm 0 trials · 3 incl. sub-types Sub-types →
- Benign laryngeal neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Subglottis neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Laryngeal neuroendocrine neoplasm 0 trials Sub-types →
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Pleural neoplasm 5 trials · 97 incl. sub-types
5 sub-types
- Pleural mesothelioma 28 trials · 86 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Benign neoplasm of pleura 0 trials Sub-types →
- Neurilemmoma of the pleura 0 trials
- Pleural solitary fibrous tumor 0 trials Sub-types →
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Bronchial neoplasm 20 trials · 38 incl. sub-types
5 sub-types
- Bronchus cancer 3 trials · 26 incl. sub-types Sub-types →
- Bronchial endocrine tumor 4 trials
- Bronchus adenoma 0 trials Sub-types →
- Endobronchial leiomyoma 0 trials
- Endobronchial lipoma 0 trials
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Nasal cavity neoplasm 1 trial · 15 incl. sub-types
3 sub-types
- Nasal cavity cancer 5 trials · 14 incl. sub-types Sub-types →
- Benign neoplasm of nasal cavity 1 trial Sub-types →
- Nasal cavity inverting papilloma 0 trials
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SMARCA4-deficient sarcoma of thorax 8 trials
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Trachea neoplasm 2 trials · 5 incl. sub-types
2 sub-types
- Benign neoplasm of trachea 0 trials · 2 incl. sub-types Sub-types →
- Tracheal cancer 0 trials · 1 incl. sub-types Sub-types →
Most studied deeper sub-types
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New hope for KRAS lung cancer: major trial launches for targeted combo therapy
Disease control Recruiting nowThis global study is testing whether adding the experimental drug olomorasib to standard immunotherapy and chemotherapy can help people with a specific genetic subtype of advanced non-small cell lung cancer (KRAS G12C mutation). About 1,264 participants will receive either the ne…
Phase 3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New hope for rare lung cancer: targeted drug trial launches
Disease control Recruiting nowThis study tests a new drug, firmonertinib, against two standard treatments for people with advanced non-small-cell lung cancer that has certain rare genetic changes (EGFR PACC mutations). About 480 participants who have not had prior treatment for advanced disease will be random…
Phase 3 • Sponsor: ArriVent BioPharma, Inc. • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New combo therapy aims to control returning lung cancer in targeted patients
Disease control Recruiting nowThis study is for people with a specific type of lung cancer (EGFR-mutant) that has spread to other parts of the body after they finished a previous treatment (osimertinib). The goal is to see if combining osimertinib with chemotherapy can help control the cancer for longer. Abou…
Phase 4 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New drug combo targets hard-to-treat cancers with KRAS mutation
Disease control Recruiting nowThis study tests two experimental drugs, elironrasib and daraxonrasib, given alone or together, in people with advanced solid tumors that have a specific KRAS G12C mutation. The goal is to see if the drugs are safe and can shrink or control the cancer. About 534 adults with lung,…
Phase 1/2 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New hope for lung cancer patients: maintenance drug aims to keep disease at bay
Disease control Recruiting nowThis study tests a drug called tarlatamab as a maintenance treatment for people with limited-stage small cell lung cancer who cannot receive standard combined chemotherapy and radiation. After completing chemotherapy with or without radiation, participants who have not gotten wor…
Phase 2 • Sponsor: Fundación GECP • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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New targeted drug shows promise for Hard-to-Treat cancers
Disease control Recruiting nowThis study tests a new drug called repotrectinib in people with advanced solid tumors that have certain gene changes (ALK, ROS1, or NTRK). The trial has two parts: first, finding a safe dose, and second, seeing how well the drug shrinks tumors. About 500 adults with advanced canc…
Phase 1/2 • Sponsor: Turning Point Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Can a simple inhaler shield lung cancer patients from radiation side effects?
Disease control Recruiting nowThis study tests whether taking inhaled budesonide (a steroid) twice daily during radiation therapy can reduce the severity of radiation pneumonitis—a common and serious lung inflammation—in people with non-small cell lung cancer. About 72 patients will be randomly assigned to re…
Phase 2 • Sponsor: Instituto Nacional de Cancerologia de Mexico • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Lung cancer showdown: surgery vs. radiation – which is better?
Disease control Recruiting nowThis study looks at two standard treatments for early-stage lung cancer: surgery and a precise type of radiation called stereotactic radiotherapy. About 670 veterans with stage I non-small cell lung cancer will take part. The goal is to see which treatment leads to longer surviva…
Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Blood test may personalize lung cancer therapy
Disease control Recruiting nowThis study tests whether a simple blood test (ctDNA) can help doctors decide if adding chemotherapy to the immunotherapy drug cemiplimab works better for advanced lung cancer. About 63 people with stage IV or stage IIIB/C non-small cell lung cancer that hasn't been treated before…
Phase 2 • Sponsor: Fundación GECP • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Could a CPAP machine make lung cancer radiation more accurate?
Symptom relief Recruiting nowThis study tests whether a CPAP device can reduce tumor movement in lung cancer patients during stereotactic body radiation therapy (SBRT). About 30 participants will use CPAP or deep inspiration breath hold to see which better stabilizes tumors. The goal is to improve treatment …
Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Which cancer care model boosts quality of life? large trial seeks answers
Symptom relief Recruiting nowThis study compares two approaches to supportive cancer care for nearly 3,000 adults with cancer. One group gets information through email or their health record, while the other works one-on-one with a lay health worker over 12 months. The goal is to see which model better impro…
Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:26 UTC
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Can we predict and treat cancer wasting better? a new study investigates
Knowledge-focused Recruiting nowThis study is looking at why some people with advanced cancer lose weight and muscle, a condition called cachexia. Researchers will follow 800 patients with advanced lung, pancreatic, or colorectal cancer to see if there are distinct subtypes of cachexia based on symptoms, biomar…
Sponsor: Kaiser Permanente • Aim: Knowledge-focused
Last updated Aug 22, 2026 00:00 UTC
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New telehealth program aims to boost lung cancer screening in hispanic communities
Knowledge-focused Recruiting nowThis study tests a telehealth coaching program called TELESCOPE, designed to help Hispanic adults at high risk for lung cancer decide whether to get screened. The program includes a decision aid, smoking cessation support, and help navigating the screening process. Researchers wi…
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC