Blood test could guide smarter lung cancer therapy
NCT ID NCT06917573
First seen Nov 19, 2025 · Last updated Apr 29, 2026 · Updated 22 times
Summary
This study tests whether a simple blood test (ctDNA) can help doctors decide if adding chemotherapy to the immunotherapy drug cemiplimab improves survival in people with advanced non-small cell lung cancer. About 63 adults with high PDL1 levels (50% or more) who haven't had prior treatment will receive cemiplimab first. Based on their ctDNA levels after two cycles, some will also get chemotherapy. The goal is to see if this personalized approach leads to better outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital Clínico San Carlos
RECRUITINGMadrid, Madrid, 28040, Spain
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Hospital De Basurto
RECRUITINGBilbao, Bilbao, 48013, Spain
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Hospital Dr. Josep Trueta
RECRUITINGGirona, Girona, 17007, Spain
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Hospital General de Alicante
RECRUITINGAlicante, Alicante, 03010, Spain
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Hospital General de Elche
RECRUITINGElche, Alicante, 03203, Spain
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Hospital General de Valencia
RECRUITINGValencia, Valencia, 46014, Spain
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Hospital Puerta de Hierro
RECRUITINGMadrid, Madrid, 28222, Spain
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Hospital Universitari Son Llatzer
RECRUITINGPalma de Mallorca, Palma de Mallorca, 07198, Spain
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Hospital Universitari Vall d' Hebron
RECRUITINGBarcelona, Barcelona, 08035, Spain
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Hospital Universitario Dr. Negrín
RECRUITINGLas Palmas de Gran Canaria, Las Palmas, 35010, Spain
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Hospital Universitario Fundación Jiménez Díaz
RECRUITINGMadrid, Madrid, 28040, Spain
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Hospital Universitario Jerez De La Frontera
NOT_YET_RECRUITINGJerez de la Frontera, Cádiz, 11407, Spain
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Hospital Universitario Regional de Málaga
RECRUITINGMálaga, Málaga, 29010, Spain
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Hospital Universitario Salamanca
RECRUITINGSalamanca, Salamanca, 37007, Spain
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Hospital Universitario Severo Ochoa
RECRUITINGLeganés, Madrid, 28911, Spain
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Hospital Universitario Son Espases
RECRUITINGPalma de Mallorca, Mallorca, 07120, Spain
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Hospital de la Santa Creu i Sant Pau
RECRUITINGBarcelona, Barcelona, 08041, Spain
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Hospitalario Universitario A Coruña
RECRUITINGA Coruña, La Coruña, 15006, Spain
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ICO Badalona, Hospital Germans Trias i Pujol
RECRUITINGBadalona, Barcelona, 08916, Spain
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ICO Hospitalet
RECRUITINGL'Hospitalet de Llobregat, Barcelona, 08908, Spain
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Conditions
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