Respiratory system disorder
MONDO:0005087A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.
Also known as: disease of respiratory system, disease or disorder of respiratory system, disorder of respiratory system, respiratory disease, respiratory disorder, respiratory system disease, respiratory system disease or disorder, respiratory system disorder
10848 clinical trials for this condition and its sub-types, 150 tagged with Respiratory system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Respiratory system disorder
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Lower respiratory tract disorder 18 trials · 7,938 incl. sub-types
5 sub-types
- Lung disorder 251 trials · 7,078 incl. sub-types Sub-types →
- Tracheal disorder 6 trials · 1,088 incl. sub-types Sub-types →
- Bronchial disorder 19 trials · 1,010 incl. sub-types Sub-types →
- Pleural disorder 15 trials · 177 incl. sub-types Sub-types →
- Tracheobronchitis 5 trials · 55 incl. sub-types Sub-types →
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Respiratory system cancer 6 trials · 4,516 incl. sub-types
9 sub-types
- Lung cancer 1,207 trials · 3,941 incl. sub-types Sub-types →
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Larynx cancer 41 trials · 125 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Bronchus cancer 3 trials · 26 incl. sub-types Sub-types →
- Paranasal sinus cancer 4 trials · 24 incl. sub-types Sub-types →
- Nasal cavity cancer 5 trials · 14 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Tracheal cancer 0 trials · 1 incl. sub-types Sub-types →
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Respiratory tract neoplasm 32 trials · 4,437 incl. sub-types
8 sub-types
- Lung neoplasm 1,367 trials · 4,039 incl. sub-types Sub-types →
- Nasopharyngeal neoplasm 37 trials · 226 incl. sub-types Sub-types →
- Laryngeal neoplasm 72 trials · 138 incl. sub-types Sub-types →
- Pleural neoplasm 5 trials · 97 incl. sub-types Sub-types →
- Bronchial neoplasm 20 trials · 38 incl. sub-types Sub-types →
- Nasal cavity neoplasm 1 trial · 15 incl. sub-types Sub-types →
- SMARCA4-deficient sarcoma of thorax 8 trials
- Trachea neoplasm 2 trials · 5 incl. sub-types Sub-types →
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Upper respiratory tract disorder 5 trials · 1,848 incl. sub-types
10 sub-types
- Tracheal disorder 6 trials · 1,088 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Laryngeal disorder 44 trials · 259 incl. sub-types Sub-types →
- Nasal cavity disorder 3 trials · 224 incl. sub-types Sub-types →
- Pharyngitis 34 trials · 43 incl. sub-types Sub-types →
- Tonsillitis 23 trials · 27 incl. sub-types Sub-types →
- Adenoid hypertrophy 22 trials
- Epiglottitis 1 trial Sub-types →
- Acute laryngopharyngitis 0 trials
- Uvulitis 0 trials
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Respiratory tract infectious disorder 174 trials · 1,330 incl. sub-types
14 sub-types
- Pneumonia 326 trials · 610 incl. sub-types Sub-types →
- Viral respiratory tract infection 47 trials · 564 incl. sub-types Sub-types →
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Streptococcal sore throat 8 trials
- Pleural tuberculosis 7 trials Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Tuberculous fibrosis of lung 3 trials
- Laryngeal diphtheria 0 trials
- Laryngeal tuberculosis 0 trials
- Nasopharyngeal diphtheria 0 trials
- Silicotuberculosis 0 trials
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Sleep apnea syndrome 214 trials · 600 incl. sub-types
2 sub-types
- Obstructive sleep apnea syndrome 516 trials · 517 incl. sub-types Sub-types →
- Central sleep apnea syndrome 21 trials · 23 incl. sub-types Sub-types →
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Disorder of pharynx 3 trials · 596 incl. sub-types
10 sub-types
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Neoplasm of oropharynx 3 trials · 279 incl. sub-types Sub-types →
- Nasopharyngeal disorder 1 trial · 263 incl. sub-types Sub-types →
- Neoplasm of hypopharynx 0 trials · 100 incl. sub-types Sub-types →
- Takayasu arteritis 27 trials
- Tonsillitis 23 trials · 27 incl. sub-types Sub-types →
- Tonsil neoplasm 0 trials · 8 incl. sub-types Sub-types →
- Peritonsillar abscess 4 trials
- Epiglottitis 1 trial Sub-types →
- Oropharyngeal anthrax 0 trials
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Cystic fibrosis 283 trials
1 sub-type
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Allergic respiratory disease 2 trials · 218 incl. sub-types
4 sub-types
- Allergic rhinitis 96 trials · 140 incl. sub-types Sub-types →
- Allergic asthma 41 trials Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Allergic bronchopulmonary aspergillosis 15 trials Sub-types →
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Paranasal sinus disorder 12 trials · 162 incl. sub-types
7 sub-types
- Sinusitis 44 trials · 130 incl. sub-types Sub-types →
- Paranasal sinus neoplasm 5 trials · 29 incl. sub-types Sub-types →
- Maxillary sinus cholesteatoma 0 trials
- Polyp of ethmoidal sinus 0 trials
- Polyp of frontal sinus 0 trials
- Polyp of maxillary sinus 0 trials
- Polyp of sphenoidal sinus 0 trials
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Perinatal asphyxia 152 trials
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Pulmonary tuberculosis 107 trials · 110 incl. sub-types
3 sub-types
- Tuberculous fibrosis of lung 3 trials
- Primary pulmonary tuberculosis 0 trials
- Silicotuberculosis 0 trials
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Bronchopulmonary dysplasia 96 trials
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Diaphragm disorder 27 trials · 91 incl. sub-types
5 sub-types
- Congenital diaphragmatic hernia 45 trials Sub-types →
- Respiratory paralysis 20 trials
- Diaphragmatic eventration 3 trials
- Diaphragmatic malformation 1 trial
- Diaphragmitis 0 trials
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Altitude sickness 54 trials · 56 incl. sub-types
2 sub-types
- Acute mountain sickness 7 trials
- Chronic mountain sickness 3 trials
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Alpha 1-antitrypsin deficiency 44 trials
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Pertussis 39 trials
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Primary ciliary dyskinesia 34 trials
59 sub-types
- Primary ciliary dyskinesia 1 6 trials
- CFAP46-related primary ciliary dyskinesia 0 trials
- Stromme syndrome 0 trials
- Ciliary discoordination due to random ciliary orientation 0 trials
- Ciliary dyskinesia with defective radial spokes 0 trials
- Ciliary dyskinesia with excessively long cilia 0 trials
- Ciliary dyskinesia with transposition of ciliary microtubules 0 trials
- Ciliary dyskinesia, primary, 36, X-linked 0 trials
- Ciliary dyskinesia, primary, 37 0 trials
- Ciliary dyskinesia, primary, 38 0 trials
- Ciliary dyskinesia, primary, 39 0 trials
- Ciliary dyskinesia, primary, 40 0 trials
- Ciliary dyskinesia, primary, 41 0 trials
- Ciliary dyskinesia, primary, 42 0 trials
- Ciliary dyskinesia, primary, 43 0 trials
- Ciliary dyskinesia, primary, 44 0 trials
- Ciliary dyskinesia, primary, 45 0 trials
- Ciliary dyskinesia, primary, 46 0 trials
- Ciliary dyskinesia, primary, 47, and lissencephaly 0 trials
- Ciliary dyskinesia, primary, 48, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 49, without situs inversus 0 trials
- Ciliary dyskinesia, primary, 50 0 trials
- Ciliary dyskinesia, primary, 51 0 trials
- Ciliary dyskinesia, primary, 52 0 trials
- Ciliary dyskinesia, primary, 53 0 trials
- Ciliary dyskinesia, primary, 54 0 trials
- Primary ciliary dyskinesia 10 0 trials
- Primary ciliary dyskinesia 11 0 trials
- Primary ciliary dyskinesia 12 0 trials
- Primary ciliary dyskinesia 13 0 trials
- Primary ciliary dyskinesia 14 0 trials
- Primary ciliary dyskinesia 15 0 trials
- Primary ciliary dyskinesia 16 0 trials
- Primary ciliary dyskinesia 17 0 trials
- Primary ciliary dyskinesia 18 0 trials
- Primary ciliary dyskinesia 19 0 trials
- Primary ciliary dyskinesia 2 0 trials
- Primary ciliary dyskinesia 20 0 trials
- Primary ciliary dyskinesia 21 0 trials
- Primary ciliary dyskinesia 22 0 trials
- Primary ciliary dyskinesia 23 0 trials
- Primary ciliary dyskinesia 24 0 trials
- Primary ciliary dyskinesia 25 0 trials
- Primary ciliary dyskinesia 26 0 trials
- Primary ciliary dyskinesia 27 0 trials
- Primary ciliary dyskinesia 28 0 trials
- Primary ciliary dyskinesia 29 0 trials
- Primary ciliary dyskinesia 3 0 trials
- Primary ciliary dyskinesia 30 0 trials
- Primary ciliary dyskinesia 32 0 trials
- Primary ciliary dyskinesia 33 0 trials
- Primary ciliary dyskinesia 34 0 trials
- Primary ciliary dyskinesia 35 0 trials
- Primary ciliary dyskinesia 4 0 trials
- Primary ciliary dyskinesia 5 0 trials
- Primary ciliary dyskinesia 6 0 trials
- Primary ciliary dyskinesia 7 0 trials
- Primary ciliary dyskinesia 8 0 trials
- Primary ciliary dyskinesia 9 0 trials
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Severe acute respiratory syndrome 30 trials
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Infantile apnea 5 trials · 22 incl. sub-types
1 sub-type
- Apnea of prematurity 20 trials
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Recurrent respiratory papillomatosis 8 trials · 9 incl. sub-types
1 sub-type
- Laryngeal papillomatosis 1 trial
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Respiratory system benign neoplasm 1 trial · 8 incl. sub-types
15 sub-types
- Benign laryngeal neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of trachea 0 trials · 2 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Benign neoplasm of nasal cavity 1 trial Sub-types →
- Benign neoplasm of ethmoidal sinus 0 trials Sub-types →
- Benign neoplasm of frontal sinus 0 trials Sub-types →
- Benign neoplasm of hypopharynx 0 trials Sub-types →
- Benign neoplasm of maxillary sinus 0 trials Sub-types →
- Benign neoplasm of nasopharynx 0 trials
- Benign neoplasm of oropharynx 0 trials
- Benign neoplasm of pleura 0 trials Sub-types →
- Benign neoplasm of sphenoidal sinus 0 trials Sub-types →
- Benign neoplasm of tonsil 0 trials Sub-types →
- Endobronchial lipoma 0 trials
- Paranasal sinus Schneiderian papilloma 0 trials Sub-types →
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Respiratory or thoracic malformation 0 trials · 8 incl. sub-types
1 sub-type
- Thoracic malformation 1 trial · 8 incl. sub-types Sub-types →
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Pulmonary hypoplasia 7 trials
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Reactive airway disease 5 trials
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2 sub-types
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5 sub-types
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Young syndrome 2 trials
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Diffuse alveolar hemorrhage 2 trials
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Plastic bronchitis 2 trials
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Middle East respiratory syndrome 1 trial
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Bronchogenic cyst 1 trial
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3 sub-types
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16q24.1 microdeletion syndrome 0 trials
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IgG4-related mediastinitis 0 trials
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Mounier-Kuhn syndrome 0 trials
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Siegler-Brewer-Carey syndrome 0 trials
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Williams-Campbell syndrome 0 trials
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Acinar dysplasia 0 trials
3 sub-types
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Bronchiectasis and nasal polyposis 0 trials
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Congenital bronchobiliary fistula 0 trials
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Eosinophilic granuloma 0 trials
1 sub-type
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Isolated left bronchial isomerism 0 trials
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Laryngo-onycho-cutaneous syndrome 0 trials
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Mucopolysaccharidosis-plus syndrome 0 trials
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Pulmonary agenesis 0 trials
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Staphylococcal necrotizing pneumonia 0 trials
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Tracheal agenesis 0 trials
Most studied deeper sub-types
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Can a new RSV vaccine keep adults out of the hospital? 690,000 join trial
Vaccine OngoingThis massive study is testing whether the Abrysvo RSV vaccine can prevent hospitalizations due to RSV in adults aged 18 and older. Half of the 690,000 participants will receive the vaccine, while the other half will not. Researchers will track how many in each group end up hospit…
Phase 4 • Sponsor: Tor Biering-Sørensen • Aim: Vaccine
Last updated Jun 27, 2026 13:00 UTC
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Pregnancy vaccine shields newborns from RSV: Real-World data reveals impact
Vaccine OngoingThis study checks how well the ABRYSVO® vaccine protects infants from severe RSV when given to pregnant women. Researchers will look at hospital records from Argentina and Uruguay over several RSV seasons. The goal is to see if the vaccine reduces hospitalizations and severe illn…
Sponsor: Pfizer • Aim: Vaccine
Last updated Jun 27, 2026 12:34 UTC
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New COVID vaccine trial targets healthy Middle-Aged adults
Vaccine OngoingThis large study tests whether an updated Moderna COVID-19 vaccine can prevent severe COVID-19 in adults aged 50 to 64 who have no health conditions that raise their risk. About 285,000 participants will be randomly assigned to get the vaccine or not. The main goal is to see if t…
Phase 4 • Sponsor: Tor Biering-Sørensen • Aim: Vaccine
Last updated Jun 27, 2026 11:02 UTC
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Drug could slash surgeries for rare airway disease
Disease control OngoingThis phase II trial tests whether bevacizumab, a drug that blocks blood vessel growth, can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a rare condition causing wart-like growths in the airways. Participants receive 11 doses of t…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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New combo shows promise for Tough-to-Treat lung cancer
Disease control OngoingThis phase 2 trial tests a combination of two drugs—ceralasertib (a pill) and durvalumab (an infusion)—in 39 adults with advanced or metastatic non-small cell lung cancer that has worsened after standard treatments like immunotherapy and chemotherapy. The main goal is to see if t…
Phase 2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New Clot-Busting device could save lives in pulmonary embolism
Disease control OngoingThis trial is testing a device called the Aventus Thrombectomy System, which suctions out blood clots from the lungs in people with acute pulmonary embolism. The study involves 130 participants aged 18 to 80. The goal is to see if the device is safe and effective at improving blo…
Sponsor: Inquis Medical, Inc. • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New combo therapy shows promise for common lung cancer mutation
Disease control OngoingThis study looks at how well the drug osimertinib combined with chemotherapy works as the first treatment for people with advanced EGFR-mutant non-small cell lung cancer. It involves 532 adults with stage IIIB, IIIC, or IV disease who cannot have surgery or radiation. Researchers…
Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Exercise as medicine: 10-week program targets diabetes and high blood pressure in seniors
Disease control OngoingThis study looks at whether 10 weeks of regular exercise (on land or in water) can lower blood sugar and blood pressure in people aged 60 and older who have several health conditions like diabetes, high blood pressure, and arthritis. 63 volunteers will be split into two exercise …
Sponsor: Universidade do Porto • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New drug combo aims to stop lung Cancer's return
Disease control OngoingThis phase 2 trial tests two drugs, durvalumab and oleclumab, given together after standard chemoradiation in 30 people with stage III lung cancer that cannot be removed by surgery. The goal is to see if the combination can delay cancer progression. Participants must have stable …
Phase 2 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New asthma drug verekitug tested for Long-Term safety
Disease control OngoingThis study is for adults with severe asthma who finished the earlier VALIANT trial. It tests the long-term safety and effectiveness of verekitug, a drug given as a shot. About 396 people are taking part. The main goal is to see if verekitug is safe over time and if it can reduce …
Phase 2 • Sponsor: Upstream Bio Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New pill targets Hard-to-Treat cancers in early trial
Disease control OngoingThis early-phase study tests a new drug called RMC-6291 in adults with advanced cancers (lung, colon, pancreatic) that have a specific KRAS G12C mutation. The goal is to find the safest dose and see how well the drug works. About 222 participants will receive the drug by mouth, a…
Phase 1 • Sponsor: Revolution Medicines, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Asthma inhaler showdown: generic vs. Brand-Name – study pulled before start
Disease control CancelledThis study aimed to see if a generic version of the fluticasone furoate/vilanterol inhaler (Sandoz) works as well as the brand-name Breo Ellipta in adults with asthma. Participants would have stopped their usual asthma meds and used only the study inhaler or a placebo for 4 weeks…
Phase 3 • Sponsor: Sandoz • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New pill shows promise against Hard-to-Treat RET-Driven cancers
Disease control OngoingThis study tests an oral drug called selpercatinib in people with advanced solid tumors that have RET gene alterations, including certain lung, thyroid, and colon cancers. The goal is to find the best dose and see if the drug can shrink tumors. About 857 participants are enrolled…
Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New asthma drug WIN378 aims to calm lung inflammation in phase 2 trial
Disease control OngoingThis study tests a new medicine, WIN378, for adults with moderate or severe asthma. WIN378 blocks a protein that causes lung inflammation, which may improve asthma control. About 136 participants will receive either WIN378 or a placebo to check safety, how the drug works in the b…
Phase 2 • Sponsor: Windward Bio • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New hope for PAH patients: Long-Term drug safety trial opens
Disease control By invitation onlyThis study looks at the long-term safety of the drug ralinepag in people with pulmonary arterial hypertension (PAH), a serious lung condition that makes it hard to breathe. About 1,000 adults who were in earlier ralinepag studies can join. The goal is to see if the drug remains s…
Phase 3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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New oral drug shows promise for kids with rare RET-Driven cancers
Disease control OngoingThis study tests an oral drug called selpercatinib (LOXO-292) in children with advanced solid or brain tumors that have a specific RET gene change. The trial has two parts: first finding a safe dose, then measuring how many children's tumors shrink. About 36 children whose cancer…
Phase 1/2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Last-Resort drug access for rare lung cancer patients
Disease control Expanded access (ended)This program provides taletrectinib, a targeted cancer pill, to adults with advanced or metastatic ROS1-positive non-small cell lung cancer who cannot join a clinical trial or use approved treatments. Patients must have a ROS1 gene fusion and adequate organ function. The goal is …
Sponsor: Nuvation Bio Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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AI chest X-Rays could catch hidden lung disease in zambia
Diagnosis OngoingThis project tests an integrated approach to lung health in Zambia. Community and primary care clinics screen people with cough, breathlessness or other respiratory symptoms for TB, post-TB lung disease, COPD, silicosis and pneumonia. All participants get a symptom check and a di…
Sponsor: Centre for Infectious Disease Research in Zambia • Aim: Diagnosis
Last updated Sep 13, 2026 00:00 UTC
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Can a single platform predict your risk for multiple chronic diseases?
Diagnosis By invitation onlyThis pilot study is testing whether the ADEN platform can accurately identify people at risk for heart disease, respiratory problems, cancer, autoimmune conditions, and frailty. Researchers will compare the platform's risk ratings to those made by doctors. If it works, the platfo…
Sponsor: Unidad de Investigación Genética Molecular • Aim: Diagnosis
Last updated Jul 29, 2026 00:00 UTC
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Could your mattress detect sleep apnea?
Diagnosis OngoingThis study tests whether a non-contact device placed under the mattress can accurately detect sleep apnea. Researchers will compare the device's readings to standard sleep tests in 200 adults suspected of having sleep apnea. If proven reliable, this could offer a simple, low-cost…
Sponsor: Withings • Aim: Diagnosis
Last updated Jun 27, 2026 09:05 UTC
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Smart patch listens for breathing danger in opioid patients
Diagnosis By invitation onlyThis study tests a wearable device that listens to breathing sounds through a sensor on the throat. It aims to detect and predict opioid-induced respiratory depression (slow or stopped breathing) in 120 adults recovering from surgery. The device's accuracy will be compared to sta…
Sponsor: Thomas Jefferson University • Aim: Diagnosis
Last updated Jun 27, 2026 09:03 UTC
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AI-Powered breathing monitor could spot lung trouble early
Diagnosis OngoingThis study tests a new, non-invasive device called the Respiratory Diagnostic Assistant that uses artificial intelligence to monitor breathing patterns. Researchers will enroll 300 adults in emergency care who are at risk of acute respiratory failure. The goal is to see if the de…
Sponsor: University of Pernambuco • Aim: Diagnosis
Last updated Jun 26, 2026 15:47 UTC
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RSV shot for moms: does it shield newborns?
Prevention OngoingThis study checks how well the RSV vaccine (ABRYSVO) works when given to pregnant women to protect their babies from severe RSV illness. Researchers will look at health records of infants hospitalized with breathing problems in Australia. They want to see if vaccinated moms' babi…
Sponsor: Pfizer • Aim: Prevention
Last updated Jun 27, 2026 07:58 UTC
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New pill could quiet chronic cough that just Won't stop
Symptom relief OngoingThis phase 3 study tests an experimental drug called BLU-5937 (camlipixant) in about 975 adults with refractory chronic cough, including unexplained chronic cough. Participants receive either the drug or a placebo for 24 weeks, and researchers measure how much coughing decreases …
Phase 3 • Sponsor: Bellus Health Inc. - a GSK company • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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New allergy vaccine could end spring sniffles
Symptom relief OngoingThis study tests a new treatment called GNR-127 for people with seasonal allergies to birch pollen. The treatment is a protein that aims to reduce allergy symptoms like sneezing, runny nose, and itchy eyes. The trial involves 150 adults and will check for safety and how well it w…
Phase 1/2 • Sponsor: AO GENERIUM • Aim: Symptom relief
Last updated Jun 26, 2026 13:40 UTC
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Austrian study maps how lung, heart, and metabolic health interact
Knowledge-focused OngoingThe Austrian LEAD study follows a large group of people to understand how lung, heart, and metabolic health change over time. Researchers measure lung function with spirometry and track body composition and metabolic markers. By observing this group, they aim to learn how these c…
Sponsor: Ludwig Boltzmann Institute for Lung Health • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Can tailored rehabilitation ease common childhood illnesses in uzbekistan?
Knowledge-focused By invitation onlyResearchers in Uzbekistan are studying common respiratory and heart conditions in children from birth to age 15. They will analyze medical records and examine blood samples to understand immune and antioxidant function in affected children. The goal is to develop and test improve…
Early phase 1 • Sponsor: Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Can a Two-Hour chill reshape heart and brain function?
Knowledge-focused OngoingResearchers at Fudan University are testing whether sitting in a 16°C room for two hours changes heart rate, blood pressure, lung function, or thinking speed in healthy young adults. Each participant will also spend time in a comfortable 22°C room for comparison. The study measur…
Sponsor: Fudan University • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Can a 4-hour stroll by traffic strain young hearts and lungs?
Knowledge-focused OngoingResearchers in Shanghai are testing whether breathing traffic-related air pollution during a short walk affects heart and lung function. Healthy young adults will either walk along a busy road or in a traffic-free park for 4.5 hours, alternating walking and rest. The team will me…
Sponsor: Fudan University • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Can two hours in the heat stress a healthy heart and mind?
Knowledge-focused OngoingResearchers at Fudan University are testing what happens to healthy young adults when they sit in a 32°C chamber for two hours. They will measure blood vessel stiffness, lung function, and mental speed, comparing these to a day spent at a comfortable 22°C. The study aims to revea…
Sponsor: Fudan University • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Digital app may bring lung rehab to local clinics
Knowledge-focused OngoingThis study looks at whether a digital tool called TELEREHAPP can help physiotherapists in private clinics provide pulmonary rehabilitation for people with chronic lung diseases like COPD. Researchers will analyze data already collected from physiotherapists and patients to see ho…
Sponsor: ADIR Association • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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Parenting program aims to boost health in latino kids
Knowledge-focused OngoingThis study tests if a special parenting program (Attachment Biobehavioral Catch-Up) can help low-income Latino children have fewer common illnesses, better sleep, and healthier weight. About 260 mothers and their 9-month-old babies will take part. The program focuses on strengthe…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can doctor training boost lung cancer care in smaller cities?
Knowledge-focused OngoingThis study looks at whether educating doctors in small and mid-sized city hospitals can improve how they test and treat patients with advanced non-small cell lung cancer. About 1000 patients will be observed to see if more patients get the right molecular tests and targeted treat…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Ultrasound peek at diaphragm could guide breathing support
Knowledge-focused OngoingThis study observes how the diaphragm works in 100 adults with acute respiratory failure who need non-invasive breathing support or high-flow oxygen. Researchers use ultrasound to measure diaphragm movement and thickness at different support levels. The goal is to understand how …
Sponsor: Foro Internacional en Cuidado Crítico • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Robot-Assisted lung biopsy under the microscope: will it deliver?
Knowledge-focused OngoingThis study is tracking over 1,300 people who are having a lung biopsy or lesion localization with the Ion Endoluminal System, a robotic device. The goal is to see how often the device successfully gets a diagnosis and how often complications like a collapsed lung or bleeding occu…
Sponsor: Intuitive Surgical • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists seek better breath tests for lung health
Knowledge-focused By invitation onlyThis study aims to improve how breath samples are collected and analyzed to find better ways to measure lung health. Researchers will collect breath from up to 1,000 people, including healthy volunteers and those with respiratory or inflammatory conditions. No treatments or medic…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Breath-Hold trick may spare ICU patients invasive tubes
Knowledge-focused OngoingThis observational study tests whether a quick breath-hold maneuver can accurately measure how hard patients are working to breathe during noninvasive ventilation. Researchers will compare this simple test to the current standard, which requires a tube down the esophagus. If the …
Sponsor: University of Bari • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New breath test could replace painful lung scopes
Knowledge-focused By invitation onlyThis study aims to see if a simple, non-invasive breathing test can accurately measure the acidity (pH) in the airways, which is often abnormal in lung diseases. Researchers will compare results from this breath test with standard methods in 150 healthy volunteers and people with…
Phase 2 • Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC