Ultrasound peek at diaphragm could guide breathing support
NCT ID NCT06892912
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study observes how the diaphragm works in 100 adults with acute respiratory failure who need non-invasive breathing support or high-flow oxygen. Researchers use ultrasound to measure diaphragm movement and thickness at different support levels. The goal is to understand how these measurements relate to breathing improvement and the need for a breathing tube. No new treatments are tested; this is purely observational.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with acute respiratory failure in the emergency department or intensive care unit (ICU).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Hypoxemic respiratory failure (SpO2 \< 88% - PaO2 \< 60 mmHg) or hypercapnic (PaCO2 \> 40) * Need for NIMV and/or HFNC. Exclusion Criteria: * Neuromuscular disease * Pregnancy * Tracheostomy * Rib fractures * Cervical injuries * Diaphragmatic paralysis * Diaphragmatic malformations * Hemodynamic instability * Morbid obesity (BMI \> 35) * Use of sedation and neuromuscular relaxants * Pneumothorax or pneumomediastinum * Poor acoustic window * Critically ill patients with a prognosis of less than 24 hours of life Patients receiving palliative interventions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asociación Colombiana de Medicina Crítica (AMCI)
Bogota, Cundinamarca, Colombia
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Other studies related to the condition(s) this trial covers.
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