New asthma drug aims to tame lung inflammation for months

NCT ID NCT07120503

Ongoing Disease control Sponsor: Windward Bio Source: ClinicalTrials.gov ↗

First seen Jan 05, 2026 · Last updated May 24, 2026 · Updated 26 times

Summary

This study tests a new long-acting medicine called WIN378 in 136 adults with moderate or severe asthma. WIN378 blocks a protein (TSLP) that causes lung inflammation, aiming to improve asthma control and reduce flare-ups. The study measures safety, how the drug moves through the body, and markers of inflammation in breath and blood. It is not a cure, but a potential new way to manage asthma long-term.

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Contacts and locations

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Locations

WB Contracted Clinical Research Site

Los Angeles, California, 90025-7014, United States
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San Jose, California, 95117, United States
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Melbourne, Florida, 32763, United States
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Miami, Florida, 33175, United States
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White Marsh, Maryland, 21162, United States
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Stow, Massachusetts, 01775-1205, United States
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Detroit, Michigan, 48202-2608, United States
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Richfield, Minnesota, 55423-2477, United States
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St Louis, Missouri, 98119, United States
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Bellevue, Nebraska, 68123, United States
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Toledo, Ohio, 43560, United States
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Edmond, Oklahoma, 73034, United States
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Pittsburgh, Pennsylvania, 15213-3236, United States
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Charleston, South Carolina, 29420, United States
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Spartanburg, South Carolina, 29303, United States
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Austin, Texas, 78730, United States
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El Paso, Texas, 79903, United States
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McKinney, Texas, 75069-8085, United States
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San Antonio, Texas, 78229, United States
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Tyler, Texas, 75708-3154, United States
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Richmond, Virginia, 23226, United States
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Buenos Aires, Buenos Aires F.D., C1023AAB, Argentina
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Buenos Aires, Buenos Aires F.D., C1121ABE, Argentina
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Buenos Aires, Buenos Aires F.D., C1414AIF, Argentina
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Buenos Aires, Buenos Aires F.D., C1425BEN, Argentina
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Buenos Aires, Buenos Aires F.D., C1425FVH, Argentina
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Buenos Aires, Buenos Aires F.D., C1426ABP, Argentina
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Córdoba, Córdoba Province, X5003DCE, Argentina
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Paraná, Entre Ríos Province, E3102ADP, Argentina
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Rosario, Santa Fe Province, S2000BRH, Argentina
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Rosario, Santa Fe Province, S2013KZD, Argentina
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Santa Fe, Santa Fe Province, S3000ASF, Argentina
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San Miguel de Tucumán, Tucumán Province, T4000CBC, Argentina
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San Miguel de Tucumán, Tucumán Province, T4000IAP, Argentina
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San Miguel de Tucumán, Tucumán Province, T4000IFL, Argentina
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Brookvale, New South Wales, 2100, Australia
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Coffs Harbour, New South Wales, 2450, Australia
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Maroubra, New South Wales, 2035, Australia
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Miranda, New South Wales, 2228, Australia
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Wollongong, New South Wales, 2500, Australia
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Birtinya, Queensland, 4575, Australia
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North Altona, Victoria, 3025, Australia
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Sofia, Grad Sofia, 1407, Bulgaria
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Lovech, Lovech, 5500, Bulgaria
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Rousse, Ruse, 7000, Bulgaria
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Sofia, Sofia, 1233, Bulgaria
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Sofia, Sofia, 1680, Bulgaria
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Pessac, Bordeaux, 33000, France
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Dijon, Côte-dOr, 21000, France
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Montpellier, Hérault, 34090, France
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La Tronche, Isère, 38700, France
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Nantes, Loire-Atlantique, 44093, France
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Berlin, Loire-Atlantique, 10119, Germany
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München, Loire-Atlantique, 80539, Germany
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Bendorf, Rhineland-Palatinate, 56170, Germany
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Lübeck, Schleswig-Holstein, 23552, Germany
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Darmstadt, 64283, Germany
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Frankfurt am Main, 60389, Germany
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Frankfurt am Main, 60596, Germany
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Leipzig, 4347, Germany
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Mainz, 55128, Germany
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München, 81241, Germany
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Chiclana de la Frontera, Cádiz, 11139, Spain
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Madrid, Entre Ríos, 28003, Spain
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San Sebastián, Guipúzcoa, 20014, Spain
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Madrid, Madrid, 28050, Spain
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Pozuelo de Alarcón, Madrid, 28223, Spain
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Benalmádena, Málaga, 29639, Spain
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Málaga, Málaga, 29010, Spain
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Seville, Sevilla, 41012, Spain
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Linköping, Ostergotlands, 587 58, Sweden
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Malmö, Skåne County, 20512, Sweden
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Stockholm, Stockholm County, 11239, Sweden

Conditions

Explore the condition pages connected to this study.

ASTHMA (DIAGNOSIS)