New asthma drug WIN378 aims to calm lung inflammation in phase 2 trial

NCT ID NCT07120503

Ongoing Disease control Sponsor: Windward Bio Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new medicine, WIN378, for adults with moderate or severe asthma. WIN378 blocks a protein that causes lung inflammation, which may improve asthma control. About 136 participants will receive either WIN378 or a placebo to check safety, how the drug works in the body, and its effect on breathing and asthma symptoms.

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Conditions

The condition(s) this trial relates to.

asthma bronchial disorder disease lung disorder respiratory system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA (DIAGNOSIS)

Contacts and locations

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Locations

WB Contracted Clinical Research Site

Málaga, Málaga, 29010, Spain
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Seville, Sevilla, 41012, Spain
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Linköping, Ostergotlands, 587 58, Sweden
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Malmö, Skåne County, 20512, Sweden
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Stockholm, Stockholm County, 11239, Sweden
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Los Angeles, California, 90025-7014, United States
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San Jose, California, 95117, United States
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Melbourne, Florida, 32763, United States
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Miami, Florida, 33175, United States
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White Marsh, Maryland, 21162, United States
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Stow, Massachusetts, 01775-1205, United States
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Detroit, Michigan, 48202-2608, United States
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Richfield, Minnesota, 55423-2477, United States
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St Louis, Missouri, 98119, United States
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Bellevue, Nebraska, 68123, United States
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Toledo, Ohio, 43560, United States
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Edmond, Oklahoma, 73034, United States
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Pittsburgh, Pennsylvania, 15213-3236, United States
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Charleston, South Carolina, 29420, United States
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Spartanburg, South Carolina, 29303, United States
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Austin, Texas, 78730, United States
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El Paso, Texas, 79903, United States
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McKinney, Texas, 75069-8085, United States
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San Antonio, Texas, 78229, United States
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Tyler, Texas, 75708-3154, United States
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Richmond, Virginia, 23226, United States
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Buenos Aires, Buenos Aires F.D., C1023AAB, Argentina
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Buenos Aires, Buenos Aires F.D., C1121ABE, Argentina
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Buenos Aires, Buenos Aires F.D., C1414AIF, Argentina
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Buenos Aires, Buenos Aires F.D., C1425BEN, Argentina
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Buenos Aires, Buenos Aires F.D., C1425FVH, Argentina
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Buenos Aires, Buenos Aires F.D., C1426ABP, Argentina
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Córdoba, Córdoba Province, X5003DCE, Argentina
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Paraná, Entre Ríos Province, E3102ADP, Argentina
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Rosario, Santa Fe Province, S2000BRH, Argentina
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Rosario, Santa Fe Province, S2013KZD, Argentina
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Santa Fe, Santa Fe Province, S3000ASF, Argentina
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San Miguel de Tucumán, Tucumán Province, T4000CBC, Argentina
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San Miguel de Tucumán, Tucumán Province, T4000IAP, Argentina
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San Miguel de Tucumán, Tucumán Province, T4000IFL, Argentina
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Brookvale, New South Wales, 2100, Australia
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Coffs Harbour, New South Wales, 2450, Australia
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Maroubra, New South Wales, 2035, Australia
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Miranda, New South Wales, 2228, Australia
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Wollongong, New South Wales, 2500, Australia
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Birtinya, Queensland, 4575, Australia
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North Altona, Victoria, 3025, Australia
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Sofia, Grad Sofia, 1407, Bulgaria
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Lovech, Lovech, 5500, Bulgaria
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Rousse, Ruse, 7000, Bulgaria
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Sofia, Sofia, 1233, Bulgaria
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Sofia, Sofia, 1680, Bulgaria
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Pessac, Bordeaux, 33000, France
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Dijon, Côte-dOr, 21000, France
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Montpellier, Hérault, 34090, France
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La Tronche, Isère, 38700, France
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Nantes, Loire-Atlantique, 44093, France
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Berlin, Loire-Atlantique, 10119, Germany
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München, Loire-Atlantique, 80539, Germany
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Bendorf, Rhineland-Palatinate, 56170, Germany
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Lübeck, Schleswig-Holstein, 23552, Germany
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Darmstadt, 64283, Germany
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Frankfurt am Main, 60389, Germany
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Frankfurt am Main, 60596, Germany
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Leipzig, 4347, Germany
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Mainz, 55128, Germany
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München, 81241, Germany
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Chiclana de la Frontera, Cádiz, 11139, Spain
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Madrid, Entre Ríos, 28003, Spain
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San Sebastián, Guipúzcoa, 20014, Spain
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Madrid, Madrid, 28050, Spain
WB Contracted Clinical Research Site

Pozuelo de Alarcón, Madrid, 28223, Spain
WB Contracted Clinical Research Site

Benalmádena, Málaga, 29639, Spain

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