Pulmonary edema
MONDO:0006932Accumulation of fluid in the lung tissues causing disturbance of the gas exchange that may lead to respiratory failure. It is caused by direct injury to the lung parenchyma or congestive heart failure. The symptoms may appear suddenly or gradually. Suddenly appearing symptoms include difficulty breathing, feeling of suffocation, and coughing associated with frothy sputum. Gradually appearing symptoms include difficulty breathing while lying in bed, shortness of breath during activity, and weight gain (in patients with congestive heart failure).
Also known as: edema, pulmonary
65 clinical trials for this condition and its sub-types, 27 tagged with Pulmonary edema itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pulmonary edema
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High altitude pulmonary edema 5 trials
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One-Size-Fits-All oxygen may be outdated: new trial tests personalized targets
Disease control By invitation onlyThis study is testing whether giving each patient on a ventilator a personalized oxygen target (based on their unique health data) leads to better outcomes than standard care. Researchers will compare death rates and time spent on the ventilator between the two groups. The trial …
Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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AI plus ultrasound could catch heart and lung decline before it turns critical
Diagnosis By invitation onlyResearchers are testing whether artificial intelligence can combine ultrasound images with routine health data to track changes in a person's physiology over time. The study enrolls adults with heart, lung, kidney, or blood vessel conditions, as well as healthy volunteers. The go…
Sponsor: Truway Health, Inc. • Aim: Diagnosis
Last updated Sep 12, 2026 00:00 UTC
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Could a thyroid hormone boost oxygen in severe lung failure?
Symptom relief OngoingThis study tests whether giving a thyroid hormone (T3) directly into the lungs can safely improve oxygen levels in adults with acute respiratory distress syndrome (ARDS), a severe lung condition. About 68 critically ill patients on ventilators will either receive the hormone or s…
Phase 2 • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Ultrasound for all: 9,000-Patient trial tests quicker hospital stays
Knowledge-focused OngoingThis study looks at whether using a simple bedside ultrasound exam on all hospitalized patients can shorten their hospital stay. Researchers will check the heart, kidneys, liver, and lungs for common problems. The goal is to see if this routine check helps doctors make faster dec…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Ultrasound peek at diaphragm could guide breathing support
Knowledge-focused OngoingThis study observes how the diaphragm works in 100 adults with acute respiratory failure who need non-invasive breathing support or high-flow oxygen. Researchers use ultrasound to measure diaphragm movement and thickness at different support levels. The goal is to understand how …
Sponsor: Foro Internacional en Cuidado Crítico • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Breathing test may predict ventilator weaning failure
Knowledge-focused CancelledThis study aimed to see if a simple breathing test (Müller maneuver) could predict which patients on ventilators would develop fluid in their lungs during a weaning trial. The test measures changes in heart output to assess fluid status. The study was withdrawn before enrolling a…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New study aims to perfect fluid checks for kidney patients
Knowledge-focused OngoingThis study looks at better ways to check fluid levels in adults with acute kidney injury (AKI). AKI is a sudden drop in kidney function that can be made worse by too little or too much fluid. Researchers will compare different assessment methods, including physical exams and bioi…
Sponsor: University of Hertfordshire • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC