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Prion disease

MONDO:0005429

A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.

Also known as: spongiform encephalopathy

11 clinical trials for this condition and its sub-types, 5 tagged with Prion disease itself.

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Part of

↑ Brain disorder (16709) ↑ Central nervous system infectious disorder (163)

Sub-types of Prion disease

Creutzfeldt Jacob disease 4 trials · 7 incl. sub-types
3 sub-types
- Inherited Creutzfeldt-Jakob disease 5 trials
- Acquired Creutzfeldt-Jakob disease 0 trials Sub-types →
- Sporadic Creutzfeldt-Jakob disease 0 trials
Fatal familial insomnia 4 trials
Gerstmann-Straussler-Scheinker syndrome 1 trial
Huntington disease-like 1 0 trials
PrP systemic amyloidosis 0 trials
Familial Alzheimer-like prion disease 0 trials
Kuru 0 trials
Scrapie 0 trials
Spongiform encephalopathy with neuropsychiatric features 0 trials
Sporadic fatal insomnia 0 trials

Most studied deeper sub-types

Iatrogenic Creutzfeldt-Jakob disease (0) Variant Creutzfeldt-Jakob disease (0)

Including sub-types (11) Tagged with Prion disease (5)

Trials to join now! 6 Not yet finished but already full! 3 Completed 2

Prion disease

Where it sits in the disease tree

Most studied deeper sub-types

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