Primary cutaneous amyloidosis
MONDO:0015301Cutaneous amyloidosis refers to a variety of skin diseases characterized histologically by the extracellular accumulation of amyloid deposits in the dermis. Rare forms include lichen amyloidosus, X-linked reticulate pigmentary disorder, primary localized cutaneous nodular amyloidosis, and macular amyloidosis.
Also known as: primary localised cutaneous amyloidosis, primary localized cutaneous amyloidosis, PLCA, familial primary localised cutaneous amyloidosis, familial primary localized cutaneous amyloidosis, amyloidosis IX, amyloidosis familial cutaneous lichen, amyloidosis, primary localised cutaneous
8 clinical trials for this condition and its sub-types, 4 tagged with Primary cutaneous amyloidosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Primary cutaneous amyloidosis
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Lichen amyloidosis 2 trials
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3 sub-types
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Macular amyloidosis 1 trial
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Amyloidosis cutis dyschromia 0 trials
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Nodular cutaneous amyloidosis 0 trials
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Laser zaps skin amyloid deposits in rare itching disorder
Symptom relief CompletedResearchers at Tanta University are testing whether fractional CO2 laser can reduce skin amyloid deposits and itching in people with primary cutaneous amyloidosis. The trial enrolls 22 adults with confirmed disease who have not used other treatments for at least six months. Parti…
Sponsor: Tanta University • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Blue dye and red light: a new hope for itchy skin?
Symptom relief CompletedThis pilot study tested whether applying methylene blue (a dye) to skin lesions and then shining red light on them could improve skin roughness in people with lichen amyloidosis, a condition causing itchy, bumpy patches. Fifteen Asian adults with the condition received the treatm…
Sponsor: Chulalongkorn University • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Could a UV laser smooth out this rare skin condition?
Symptom relief CompletedThis pilot study tested a 308-nm excimer laser on 15 Asian adults with lichen amyloidosis, a condition that causes itchy, rough patches on the skin. The goal was to see if the laser could improve skin roughness. The study is small and early, so results are not conclusive.
Sponsor: Chulalongkorn University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Scientists track severe allergies to uncover hidden patterns
Knowledge-focused CompletedThis completed study followed 945 people, mostly children and young adults with severe eczema or related allergic conditions, along with their relatives. Researchers observed how these diseases progress over up to a year, using tests like allergy skin pricks, blood draws, and lun…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC