Could a UV laser smooth out this rare skin condition?
NCT ID NCT03068156
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested a 308-nm excimer laser on 15 Asian adults with lichen amyloidosis, a condition that causes itchy, rough patches on the skin. The goal was to see if the laser could improve skin roughness. The study is small and early, so results are not conclusive.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 308-nm excimer laser (a type of ultraviolet light)
- What this could lead to
- If it works, this could offer a new way to reduce skin roughness and improve appearance for people with lichen amyloidosis.
- What could go wrong
- This is a very small pilot study with only 15 participants, so results may not apply to everyone. The laser may not improve symptoms, and there is a risk of skin irritation or burns from UV exposure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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15 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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Mar 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients, aged \>18 years old with lichen amyloidosis diagnosed by using clinical presentation and pathologic features Exclusion Criteria: * Those with cutaneous amyloidosis associated systemic diseases * Pregnancy or lactating woman * Those who are allergic to urea, olive oil * Those who are photosensitive to ultraviolet radiation * Those who had been previously treated with medications/ radiation/ laser within 3 months for systemic and 1 month for topical therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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King Chulalongkorn Memorial Hospital
Bangkok, Bangkok, 10330, Thailand
More trials for these conditions
Other studies related to the condition(s) this trial covers.