Premature menopause

This pilot trial tests whether a drug called G-CSF, given as a short course of injections, can improve markers of ovarian reserve in women aged 25-40 with premature ovarian insufficiency (POI). The main question is whether treatment can lower FSH levels, raise AMH, and increase a…

This early-phase trial tests whether injecting tiny particles called extracellular vesicles, derived from bone marrow stem cells, directly into the ovary is safe for women with premature ovarian failure. The study includes 10 women aged 20–38 who have had no menstrual period for …

This study followed 86 women under 40 with premature ovarian failure (early menopause) who had received a one-time gene therapy using their own stem cells. The goal was to check long-term safety and see if hormone levels and fertility improved over 2.5 years. No new treatment was…

This study tested whether platelet-rich plasma from umbilical cord blood can thicken the endometrium (uterine lining) in women with Asherman's syndrome or endometrial atrophy. Fifteen women received an injection of the plasma into the uterine wall during a hysteroscopy, along wit…

This study tested an online nurse-led program to help young women who had breast cancer improve their sexual health, body image, and menopausal symptoms. 43 women who finished treatment within the last five years took part in eight weekly sessions. The program aimed to see if it …

This study tested whether paroxetine, a common antidepressant, can reduce hot flashes and night sweats in women who entered menopause after surgery. 90 women took either paroxetine or a placebo daily for 6 months. The goal was to see if paroxetine could be a safer alternative to …

This study follows 135 women with premature ovarian failure (early menopause) to see if hormone replacement therapy improves their sexual quality of life. Participants fill out questionnaires about sexual function and well-being before starting treatment and again 6 months later.…