Pneumococcal meningitis
MONDO:0006913An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with otitis media; mastoiditis; sinusitis; respiratory tract infections; sickle cell disease (anemia, sickle cell); skull fractures; and other disorders. Clinical manifestations include fever; headache; neck stiffness; and somnolence followed by seizures; focal neurologic deficits (notably deafness); and coma. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)
Also known as: Streptococcus pneumoniae caused infectious meningitis, Streptococcus pneumoniae infectious meningitis
11 clinical trials for this condition and its sub-types, 0 tagged with Pneumococcal meningitis itself.
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New 24-Strain pneumonia vaccine enters human trials
Vaccine Recruiting nowThis study tests a new vaccine (PCV24) designed to protect against 24 types of pneumococcal bacteria, which can cause pneumonia, meningitis, and ear infections. The trial includes 854 healthy people aged 2 months and older, split into two phases to check safety and immune respons…
Phase 1/2 • Sponsor: CanSino Biologics Inc. • Aim: Vaccine
Last updated Aug 07, 2026 00:00 UTC
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Can you get the pneumonia shot while sick? new study finds out
Vaccine Recruiting nowThis study looks at whether giving the 20-valent pneumococcal vaccine (PCV-20) to adults while they have a fever is as effective and safe as waiting until they are well. About 1052 adults with certain health risks (like heart or lung disease) will take part. The goal is to see if…
Phase 4 • Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Vaccine
Last updated Jun 27, 2026 12:02 UTC
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Rapid brain infection test could slash unnecessary antibiotic use
Diagnosis Recruiting nowThis study looks at whether a quick diagnostic test (BioFire FilmArray) can accurately predict the cause of meningitis or encephalitis in 182 adults. Participants with symptoms like fever, headache, or confusion will have their spinal fluid tested. The goal is to see if the test …
Sponsor: Federal University of Health Science of Porto Alegre • Aim: Diagnosis
Last updated Aug 23, 2026 00:00 UTC
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Massive meningitis study aims to save lives in uganda
Knowledge-focused Recruiting nowThis study in northern Uganda will track 1,100 people with meningitis symptoms and screen 10,000 HIV-positive patients for a fungal infection that can lead to meningitis. Researchers will use modern diagnostic tests to understand the causes and outcomes of the disease. The goal i…
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Massive meningitis study aims to improve care in brazil
Knowledge-focused Recruiting nowThis study is tracking how adults with meningitis are treated in about 30 hospitals across Brazil. Researchers will follow 624 patients during their hospital stay and after discharge to see what treatments work best and how patients recover. The goal is to gather real-world evide…
Sponsor: Hospital Israelita Albert Einstein • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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New registry aims to improve meningitis treatment for kids
Knowledge-focused Recruiting nowThis study is creating a registry of 600 children under 18 with meningitis treated at hospitals across Brazil. Researchers will collect data during and after hospitalization to see how well current treatments work and what long-term problems, like hearing loss, occur. The goal is…
Sponsor: Hospital Israelita Albert Einstein • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC