Pleural disorder
MONDO:0002037A non-neoplastic or neoplastic disorder that affects the pleura. Representative examples include pleural infection, pleural mesothelioma, and pleural solitary fibrous tumor.
Also known as: disease of pleura, disease or disorder of pleura, disorder of pleura, pleura disease, pleura disease or disorder, pleural disorder, pleural disorders, non-neoplastic pleural disease
177 clinical trials for this condition and its sub-types, 15 tagged with Pleural disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Pleural disorder
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Pleural neoplasm 5 trials · 97 incl. sub-types
5 sub-types
- Pleural mesothelioma 28 trials · 86 incl. sub-types Sub-types →
- Pleural cancer 9 trials · 83 incl. sub-types Sub-types →
- Benign neoplasm of pleura 0 trials Sub-types →
- Neurilemmoma of the pleura 0 trials
- Pleural solitary fibrous tumor 0 trials Sub-types →
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Pneumothorax 35 trials · 45 incl. sub-types
5 sub-types
- Familial spontaneous pneumothorax 13 trials
- Hemopneumothorax 2 trials
- Spontaneous tension pneumothorax 1 trial
- Catamenial pneumothorax 0 trials
- Tuberculous pneumothorax 0 trials
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Pleural empyema 20 trials
1 sub-type
- Tuberculous empyema 0 trials
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Pleurisy 2 trials · 9 incl. sub-types
2 sub-types
- Pleural tuberculosis 7 trials Sub-types →
- Pleuropneumonia 0 trials
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Congenital chylothorax 0 trials
Most studied deeper sub-types
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Keyhole surgery may beat standard care for chest infections
Disease control Not yet recruitingThe PROMPT study is testing whether an early keyhole procedure called medical thoracoscopy works better than current standard treatment (medicines to break up thick fluid) for people with pleural infection. About 170 patients will be randomly assigned to one of the two treatments…
Sponsor: Università Politecnica delle Marche • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New flexible scope aims to make lung lining diagnosis easier and more accurate
Diagnosis Not yet recruitingThis trial tests a new dual-function semirigid thoracoscope against the standard rigid thoracoscope for diagnosing pleural disease (fluid buildup around the lungs). The new device is designed to be easier to maneuver and potentially less painful while still obtaining large tissue…
Sponsor: China-Japan Friendship Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 14:01 UTC
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New ultrasound method could replace invasive lung biopsy for fluid diagnosis
Diagnosis Not yet recruitingThis study tests whether starting with a less invasive ultrasound-guided biopsy can match the accuracy of immediate thoracoscopy (a camera-guided biopsy) for diagnosing unexplained fluid around the lungs. 420 adults with this condition will be randomly assigned to either the step…
Sponsor: China-Japan Friendship Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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New nerve block technique could reduce opioid use in lung exams
Symptom relief Not yet recruitingThis study tests whether an ultrasound-guided nerve block (erector spinae plane block) provides better pain relief than standard local anesthesia during a lung procedure called medical thoracoscopy. One hundred adults scheduled for this procedure will be randomly assigned to rece…
Phase 2/3 • Sponsor: Kafrelsheikh University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Can a simple ultrasound spot muscle loss in liver disease?
Knowledge-focused Not yet recruitingThis observational study will use bedside ultrasound to measure the diaphragm—the main breathing muscle—in 120 adults with liver cirrhosis and compare them to healthy volunteers. Researchers want to see if cirrhosis weakens the diaphragm and if removing fluid from the belly impro…
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC