Phosphorus metabolism disease

This study looks at whether adding tenapanor to standard phosphate binders helps people on hemodialysis lower their blood phosphorus levels. High phosphorus is common in dialysis patients and can lead to bone and heart problems. The trial will follow about 200 adults who are alre…

This study investigates whether changes in serum phosphate, a blood electrolyte, are linked to respiratory quotient, a measure of how the body uses energy, in critically ill patients during their first week in intensive care. The goal is to see if a rising respiratory quotient co…

This study will take 3D scans of the inside of the mouth from 240 people with rare bone or cartilage diseases and from healthy volunteers. Researchers will use shape analysis and artificial intelligence to see if these scans can help tell different diseases apart. The goal is to …

This study will compare two standard approaches for replacing phosphate in critically ill patients in the intensive care unit (ICU). One approach starts replacement at a higher phosphate level (liberal), the other at a lower level (restrictive). The goal is to see if the restrict…