Phagocytic cell dysfunction
MONDO:0024627Also known as: defective phagocytosis, phagocytic cell dysfunction
76 clinical trials for this condition and its sub-types, 1 tagged with Phagocytic cell dysfunction itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Phagocytic cell dysfunction
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Langerhans cell histiocytosis 39 trials · 40 incl. sub-types
8 sub-types
- Langerhans cell histiocytosis specific to childhood 1 trial Sub-types →
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
- Eosinophilic granuloma 0 trials Sub-types →
- Hand-Schuller-Christian disease 0 trials
- Multisystem langerhans cell histiocytosis 0 trials
- Pulmonary langerhans cell histiocytosis 0 trials
- Single-system multifocal langerhans cell histiocytosis 0 trials
- Unifocal langerhans cell histiocytosis 0 trials
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Defective phagocytic cell engulfment 0 trials · 37 incl. sub-types
5 sub-types
- Chronic granulomatous disease 37 trials Sub-types →
- Inherited glutathione synthetase deficiency 1 trial Sub-types →
- Myeloperoxidase deficiency 1 trial
- Gluthathione peroxidase deficiency 0 trials
- Specific granule deficiency 0 trials Sub-types →
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Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types
1 sub-type
- Chronic granulomatous disease 37 trials Sub-types →
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Defective phagocytic cell chemotaxis 0 trials
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Familial lipochrome histiocytosis 0 trials
Most studied deeper sub-types
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Gene fix for rare immune disease: can it stop deadly infections?
Disease control Not yet recruitingThis trial tests a gene therapy for chronic granulomatous disease (CGD), a rare immune disorder that leaves patients vulnerable to severe infections. Ten patients will receive their own stem cells modified with a lentivirus to correct the faulty gene. The goal is to restore immun…
Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can a targeted pill tame a rare immune disease?
Disease control Not yet recruitingThis phase 2 trial is testing whether the experimental drug luvometinib, taken alone or with the chemotherapy drug cytarabine, can control Langerhans cell histiocytosis—a rare disease where immune cells build up and damage tissues. People aged 10 and older who need systemic treat…
Phase 2 • Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University • Aim: Disease control
Last updated Jul 29, 2026 00:00 UTC
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500 patients to help unlock secrets of rare histiocytosis disorders
Knowledge-focused Not yet recruitingThis study will collect blood, saliva, urine, and stool samples from 500 adults with systemic histiocytosis—a group of rare inflammatory disorders. Researchers aim to identify biomarkers that could improve diagnosis, predict disease progression, and enable less invasive monitorin…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:07 UTC