Phagocytic cell dysfunction
MONDO:0024627Also known as: defective phagocytosis, phagocytic cell dysfunction
77 clinical trials for this condition and its sub-types, 1 tagged with Phagocytic cell dysfunction itself.
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Sub-types of Phagocytic cell dysfunction
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Langerhans cell histiocytosis 40 trials · 41 incl. sub-types
8 sub-types
- Langerhans cell histiocytosis specific to childhood 1 trial Sub-types →
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
- Eosinophilic granuloma 0 trials Sub-types →
- Hand-Schuller-Christian disease 0 trials
- Multisystem langerhans cell histiocytosis 0 trials
- Pulmonary langerhans cell histiocytosis 0 trials
- Single-system multifocal langerhans cell histiocytosis 0 trials
- Unifocal langerhans cell histiocytosis 0 trials
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Defective phagocytic cell engulfment 0 trials · 37 incl. sub-types
5 sub-types
- Chronic granulomatous disease 37 trials Sub-types →
- Inherited glutathione synthetase deficiency 1 trial Sub-types →
- Myeloperoxidase deficiency 1 trial
- Gluthathione peroxidase deficiency 0 trials
- Specific granule deficiency 0 trials Sub-types →
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Phagocyte bactericidal dysfunction 0 trials · 37 incl. sub-types
1 sub-type
- Chronic granulomatous disease 37 trials Sub-types →
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Defective phagocytic cell chemotaxis 0 trials
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Familial lipochrome histiocytosis 0 trials
Most studied deeper sub-types
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Experimental gene therapy aims to fix immune system in rare childhood disease
Disease control Stopped earlyThis early-phase trial tested a gene therapy for X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder that leaves boys unable to fight off bacteria and fungi. The treatment involved taking the patient's own blood stem cells, adding a corrected gene, and infusin…
Phase 1/2 • Sponsor: Genethon • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Experimental gene therapy targets rare immune disorder
Disease control Stopped earlyThis trial tested a gene therapy for X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder that leaves boys unable to fight off infections. The treatment involved taking the patient's own blood stem cells, adding a working copy of the faulty gene, and returning …
Phase 1/2 • Sponsor: Genethon • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC