Pertussis
MONDO:0005077A contagious bacterial respiratory infection caused by Bordetella pertussis. It is characterized by severe and uncontrollable cough, resulting in a whooping sound during breathing following the cough.
Also known as: Bordetella infection, Bordetella pertussis caused disease or disorder, Bordetella pertussis disease or disorder, Bordetella pertussis infection, Bordetella pertussis infectious disease, pertussis, whooping cough, infection due to Bordetella pertussis
47 clinical trials for this condition and its sub-types, 39 tagged with Pertussis itself.
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One shot, six protections: could a single vaccine replace multiple infant shots?
Vaccine OngoingThis trial tests a new vaccine called LBVD, which combines protection against six diseases: diphtheria, tetanus, whooping cough, hepatitis B, polio, and Hib. The study enrolls healthy infants around 6 to 8 weeks old who receive three doses at 6, 10, and 14 weeks of age. Researche…
Phase 2/3 • Sponsor: LG Chem • Aim: Vaccine
Last updated Sep 05, 2026 00:00 UTC
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Whooping cough vaccine safety checked in 2,700 thai moms and babies
Vaccine OngoingThis study reviews medical records of about 2,700 pregnant women in Thailand who received the Pertagen® whooping cough vaccine and their babies. Researchers want to see if the vaccine is linked to any delivery complications or health issues in newborns. The goal is to confirm the…
Sponsor: BioNet-Asia Co., Ltd. • Aim: Vaccine
Last updated Jun 27, 2026 07:53 UTC
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New whooping cough vaccine passes major safety check in thousands of adults
Vaccine OngoingThis large Phase 3 trial is testing the safety of a new recombinant pertussis (whooping cough) vaccine in 2,399 healthy adults aged 18 to 75. Participants receive a single booster dose, and researchers monitor for side effects over 28 days. The goal is to confirm the vaccine is s…
Phase 3 • Sponsor: BioNet-Asia Co., Ltd. • Aim: Vaccine
Last updated Jun 27, 2026 07:53 UTC
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New infant vaccine aims to shield against three serious diseases
Vaccine OngoingThis phase 3 study tests a new vaccine (DTacP) that protects infants from diphtheria, tetanus, and whooping cough. Around 2,900 healthy babies aged 2-3 months will receive the vaccine to check its safety and how well it triggers immunity. The trial compares different schedules an…
Phase 3 • Sponsor: China National Biotec Group Company Limited • Aim: Vaccine
Last updated Jun 26, 2026 17:26 UTC
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New tetracycline drugs take on superbugs in Real-World trial
Disease control By invitation onlyThis real-world study is testing two neotetracycline drugs, eravacycline and tigecycline, in 300 adults with drug-resistant Gram-negative bacterial infections. Researchers will track how well the drugs clear the infection and monitor for side effects. The goal is to see if these …
Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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One shot in pregnancy could shield babies from whooping cough
Prevention OngoingThis phase 3 trial will give a single dose of the dTpa vaccine (Boostrix) to 95 healthy Japanese pregnant women between 27 and 37 weeks of pregnancy. The goal is to see if the vaccine triggers strong immunity in the mothers and passes protective antibodies to their babies at birt…
Phase 3 • Sponsor: GlaxoSmithKline • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
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Can a booster shot stop whooping cough bacteria in its tracks?
Knowledge-focused OngoingThis study looks at whether a booster dose of the acellular pertussis vaccine (Tdap-IPV) can reduce the amount of whooping cough bacteria in the nose after intentional exposure. Healthy adults who were vaccinated as children will receive either the Tdap-IPV booster or a control v…
Phase 4 • Sponsor: Dimitri Diavatopoulos • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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500 kids tracked daily to unlock secrets of winter viruses
Knowledge-focused OngoingThis study follows 500 children under 18 who tested positive for flu, RSV, or COVID-19. Each child takes a daily nose swab for 14 days to measure how the virus levels change over time. Researchers also check if family members get sick. The goal is to understand when kids are most…
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Massive U.S. study to see if whooping cough vaccine is safe for pregnant women and babies
Knowledge-focused OngoingThis study is using electronic medical records from about 365,000 pregnant women in the U.S. to check the safety of the Adacel vaccine, which protects against tetanus, diphtheria, and whooping cough. Researchers will compare pregnancy and birth outcomes between women who got the …
Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC