500 kids tracked daily to unlock secrets of winter viruses
NCT ID NCT06640387
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 500 children under 18 who tested positive for flu, RSV, or COVID-19. Each child takes a daily nose swab for 14 days to measure how the virus levels change over time. Researchers also check if family members get sick. The goal is to understand when kids are most contagious and how these viruses spread at home and school, which could lead to smarter quarantine rules.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could provide better guidelines on when children with respiratory infections are contagious, helping schools and families reduce spread.
- What could go wrong
- This is an observational study, not a treatment trial. It won't directly cure or prevent illness, and results may not apply to all settings or future virus strains.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2024
- Expected to finish
-
May 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Individuals with acute symptomatic influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis infection identified through hospital testing (inpatient, outpatient, staff household members) or the school-based take-home saliva testing program.
- Ages
-
1 day and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Viral dynamics (primary outcome): * The child must be less than 18 years of age * Have a positive PCR sample for influenza, RSV or SARS-CoV-2, * Have any one of the symptoms listed to meet testing eligibility: fever, cough, shortness of breath, decreased or loss of taste or smell, muscle aches/joint pains (unusual, long lasting, not related to injury), extreme tiredness (unusual fatigue not otherwise explained), sore throat, runny or stuffy/congested nose, headache (new, unusual, long-lasting), nausea/vomiting and/or diarrhea, and * Be within 5 days of symptom onset Household testing inclusion criteria (secondary outcome): -Any individual in the same household (i.e. household contacts, defined as residing at the same address) as the individual testing positive by PCR for influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis Classroom testing inclusion criteria (secondary outcome): -Any individual in the same classroom (i.e. classroom contacts) as the individual testing positive by PCR for influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis (i.e. case identified through the THS program) Exclusion Criteria: Viral dynamics (primary outcome): -Participants will be ineligible if they are more than 5 days from symptom onset
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bordetella pertussis, whooping cough are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Hospital for Sick Children (SickKids)
Toronto, Ontario, M5G 1X8, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- How long does RSV protection last in a Baby's nose?
- Can a pill stop COVID-19 before it starts?
- Why COVID-19 hits blood cancer patients harder: scientists map the immune clues
- When the immune system Can't fight back: tracking three respiratory viruses
- Flu's journey: scientists track how influenza passes between people
- The household maze: how does COVID-19 move between family members?