Peripheral vascular disease

This study tests whether virtual group visits—where patients meet online for diabetes education, support, and goal setting—can improve blood sugar control in people with type 2 diabetes who also have heart-related conditions. About 720 adults from participating clinics will take …

This study compares a paclitaxel-coated balloon (Legflow DCB) to a standard uncoated balloon for treating blocked leg arteries in people with peripheral artery disease. About 150 participants with moderate to severe symptoms will be randomly assigned to one of the two treatments.…

This study tests whether applying shockwave therapy to the calf muscles can improve blood flow and reduce pain in people with peripheral artery disease. About 138 adults with stable leg pain when walking will receive the treatment. The goal is to see if it helps them walk longer …

This study tests whether using a far red light device on the legs for 10 minutes twice a day can improve walking distance in people with peripheral artery disease (PAD). The trial involves 32 adults aged 50 and older with PAD. Participants use the light at home for four months, a…

This early study tests whether a combination of arginine, tetrahydrobiopterin, and vitamin C can boost nitric oxide levels in the blood and help people with peripheral artery disease walk longer without pain. Ten participants will take the therapy and be monitored for changes in …

This study tests a simple, passive leg movement called LEAP therapy in people with peripheral artery disease (PAD). Participants sit for 2.5 hours with or without the leg movement, and researchers measure blood flow, walking ability, and other health markers. The goal is to see i…

This study surveys doctors who use Concerto Versa detachable coils to treat various blood vessel conditions like aneurysms and varicose veins. About 30 patients will be included, and doctors report how well the coils work and any problems within 72 hours. The goal is to collect e…

This study is a registry that collects safety and performance data on the GORE® VIABAHN® VBX Stent Graft when used in peripheral vessels. It involves 280 adults who need this device to treat peripheral vascular disease. The goal is to see how well the stent graft works and if the…

This study was designed to see if a cholesterol-lowering drug called a PCSK9 inhibitor could also reduce inflammation in the arteries of people with heart disease. Researchers planned to use a special imaging scan to measure inflammation. The study was withdrawn before enrolling …