Overgrowth syndrome
MONDO:0019716A group of syndromes caused by genetic birth defects that may lead to the development of malignancies. It is characterized by a large body size or large body parts at birth, or excessive body growth early in childhood. Representative examples include neurofibromatosis, Beckwith-Wiedemann syndrome, and Sturge-Weber syndrome.
49 clinical trials for this condition and its sub-types, 1 tagged with Overgrowth syndrome itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Overgrowth syndrome
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PIK3CA-related overgrowth spectrum 15 trials · 19 incl. sub-types
5 sub-types
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Simpson-Golabi-Behmel syndrome 11 trials
2 sub-types
- Simpson-Golabi-Behmel syndrome type 1 0 trials
- Simpson-Golabi-Behmel syndrome type 2 0 trials
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Beckwith-Wiedemann syndrome 6 trials
8 sub-types
- Beckwith-Wiedemann syndrome due to 11p15 microdeletion 0 trials
- Beckwith-Wiedemann syndrome due to 11p15 microduplication 0 trials
- Beckwith-Wiedemann syndrome due to 11p15 translocation/inversion 0 trials
- Beckwith-Wiedemann syndrome due to CDKN1C mutation 0 trials
- Beckwith-Wiedemann syndrome due to NSD1 mutation 0 trials
- Beckwith-Wiedemann syndrome due to imprinting defect of 11p15 0 trials
- Beckwith-Wiedemann syndrome due to paternal uniparental disomy of chromosome 11 0 trials
- Franceschini Vardeu Guala syndrome 0 trials
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Angioosteohypertrophic syndrome 6 trials
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Hemifacial hypertrophy 5 trials
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Maffucci syndrome 2 trials
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Proteus syndrome 2 trials
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Congenital isolated hyperinsulinism 0 trials · 2 incl. sub-types
4 sub-types
- Diazoxide-sensitive diffuse hyperinsulinism 0 trials · 2 incl. sub-types Sub-types →
- Hyperinsulinemic hypoglycemia, familial, 2 1 trial Sub-types →
- Diazoxide-resistant hyperinsulinism 0 trials Sub-types →
- Hyperinsulinemic hypoglycemia, familial, 3 0 trials
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11p15.4 microduplication syndrome 0 trials
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15q overgrowth syndrome 0 trials
2 sub-types
- Distal tetrasomy 15q 0 trials
- Distal trisomy 15q 0 trials
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4p16.3 microduplication syndrome 0 trials
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AKT3-related overgrowth spectrum 0 trials
1 sub-type
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CLAPO syndrome 0 trials
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MTOR-related overgrowth spectrum 0 trials
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Malan overgrowth syndrome 0 trials
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Marshall-Smith syndrome 0 trials
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PIK3R2-related overgrowth spectrum 0 trials
1 sub-type
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Perlman syndrome 0 trials
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Weaver syndrome 0 trials
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Hemifacial myohyperplasia 0 trials
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Isolated hemihyperplasia 0 trials
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Tetrasomy 12p 0 trials
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Trisomy 5p 0 trials
Most studied deeper sub-types
Exercise-induced hyperinsulinism
(1)
Hyperinsulinism-hyperammonemia syndrome
(1)
Autosomal dominant hyperinsulinism due to Kir6.2 deficiency
(0)
Autosomal dominant hyperinsulinism due to SUR1 deficiency
(0)
Autosomal recessive hyperinsulinism due to Kir6.2 deficiency
(0)
Autosomal recessive hyperinsulinism due to SUR1 deficiency
(0)
Diazoxide-resistant diffuse hyperinsulinism
(0)
Diazoxide-resistant focal hyperinsulinism
(0)
Diazoxide-resistant focal hyperinsulinism due to Kir6.2 deficiency
(0)
Diazoxide-resistant focal hyperinsulinism due to SUR1 deficiency
(0)
Hyperinsulinemic hypoglycemia, familial, 4
(0)
Hyperinsulinism due to HNF1A deficiency
(0)
Hyperinsulinism due to HNF4A deficiency
(0)
Hyperinsulinism due to UCP2 deficiency
(0)
Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3
(0)