Exercise-induced hyperinsulinism

MONDO:0012396

Exercise-induced hyperinsulinism (EIHI) is a form of diazoxide-sensitive diffuse hyperinsulinism (DHI) characterized by episodes of hypoglycemia induced by exercise due to an inappropriate lactate and pyruvate sensitivity in pancreatic beta-cells.

Also known as: EIHI, MCT1 hyperinsulinism, exercise-induced hyperinsulinemic hypoglycemia, hyperinsulinemic hypoglycemia, familial, type 7, hyperinsulinism due to SLC16A1 deficiency, hyperinsulinism due to monocarboxylate transporter 1 deficiency, monocarboxylate transporter 1 hyperinsulinism, HHF7

1 clinical trial for this condition and its sub-types, 1 tagged with Exercise-induced hyperinsulinism itself.

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Where it sits in the disease tree

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Part of

↑ Disorder of carbohydrate transmembrane transport and absorption (162) ↑ Diazoxide-sensitive diffuse hyperinsulinism (2)

Including sub-types (1) Tagged with Exercise-induced hyperinsulinism (1)

Trials to join now! 1

Could a tiny glucagon shot before workout stop blood sugar crashes in type 1 diabetes?

Disease control Recruiting now

This study tests whether a low dose of glucagon, given before exercise, can prevent blood sugar drops in adults with type 1 diabetes who use an automated insulin pump. Eighteen participants will exercise after a meal, comparing glucagon to a standard glucose drink. The goal is to…

Phase 4 • Sponsor: Steno Diabetes Center Copenhagen • Aim: Disease control

Last updated Aug 15, 2026 00:00 UTC

Exercise-induced hyperinsulinism

Where it sits in the disease tree

Could a tiny glucagon shot before workout stop blood sugar crashes in type 1 diabetes?