Osteonecrosis
MONDO:0005380A none disease characterized by death of bone tissue due to a lack of blood supply.
Also known as: bone necrosis, ischaemic bone disease, ischemic bone disease, osteonecrosis
224 clinical trials for this condition and its sub-types, 59 tagged with Osteonecrosis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Osteonecrosis
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Avascular necrosis 80 trials · 141 incl. sub-types
3 sub-types
- Primary avascular necrosis 0 trials · 39 incl. sub-types Sub-types →
- Secondary avascular necrosis 1 trial · 38 incl. sub-types Sub-types →
- Dysbaric osteonecrosis 0 trials
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Osteonecrosis of genetic origin 0 trials · 102 incl. sub-types
12 sub-types
- Familial avascular necrosis of femoral head 20 trials · 39 incl. sub-types Sub-types →
- Scheuermann disease 24 trials
- Osteochondritis dissecans 20 trials
- Gaucher disease type I 12 trials
- Legg-Calve-Perthes disease 9 trials
- Dihydropyrimidine dehydrogenase deficiency 3 trials
- Epiphysiolysis of the hip 3 trials
- Hereditary antithrombin deficiency 3 trials
- Thiemann disease, familial form 0 trials
- Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency 0 trials
- Pseudohypoparathyroidism type 1C 0 trials
- Short stature and advanced bone age, with or without early-onset osteoarthritis and/or osteochondritis dissecans 0 trials
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Osteochondrosis 8 trials · 46 incl. sub-types
11 sub-types
- Scheuermann disease 24 trials
- Legg-Calve-Perthes disease 9 trials
- Osgood-Schlatter disease 5 trials
- Dihydropyrimidine dehydrogenase deficiency 3 trials
- Kienbock disease 1 trial
- Osteochondritis of tarsal/metatarsal bone 1 trial
- Freiberg disease 0 trials
- Sinding-Larsen-Johansson disease 0 trials
- Thiemann disease, familial form 0 trials
- Medial condensing osteitis of the clavicle 0 trials
- Panner disease 0 trials
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Osteoradionecrosis 14 trials · 15 incl. sub-types
1 sub-type
- Osteoradionecrosis of the mandible 5 trials
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Dieterich disease 1 trial
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Kummell disease 1 trial
Most studied deeper sub-types
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Can a new hip implant stand the test of time?
Disease control Stopped earlyThis study follows about 300 people who receive a hip replacement using the GTS cementless stem, a type of implant that anchors to bone without cement. The goal is to see how well the implant performs over up to 10 years, measuring pain, function, and joint stability. Participant…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Shoulder implant under review: will it last 10 years?
Disease control Stopped earlyThis study looked at a shoulder implant used to treat pain and joint problems from conditions like arthritis, fractures, and rotator cuff tears. It involved 67 adults who received the implant and tracked how long it lasted and any side effects over 10 years. The goal was to confi…
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New shoulder implant tested for severe arthritis – but study halted early
Disease control Stopped earlyThis study looked at the TITAN Reverse Shoulder System, a device used to replace the shoulder joint in people with severe arthritis and a torn rotator cuff. The goal was to see if it relieves pain and improves movement. About 151 people were planned to take part, but the study wa…
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Knee implant study halted early: what we know
Disease control Stopped earlyThis study looked at how well the P.F.C. Sigma knee replacement implant works in people with severe knee arthritis. Researchers planned to follow 723 patients for at least 5 years after surgery, tracking pain, function, and any complications. However, the study was terminated ear…
Phase 4 • Sponsor: DePuy International • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Oxygen chamber therapy tested for jaw bone decay after cancer radiation
Disease control Stopped earlyThis study looked at whether breathing pure oxygen in a pressure chamber (hyperbaric oxygen therapy) can help heal jaw damage caused by radiation treatment for cancer. The trial planned to include 20 people with jaw bone decay, but it was stopped early. The goal was to see if the…
Phase 2/3 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated Jun 26, 2026 17:05 UTC
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New hip implant put to the test: will it stay put?
Knowledge-focused Stopped earlyThis study looked at a specific hip implant shell (the Pinnacle Acetabular Shell) used in total hip replacement. Researchers wanted to see how much the implant moved (migrated) over two years using a special X-ray technique called RSA. They also tracked how patients felt and func…
Sponsor: DePuy Orthopaedics • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC