Oxygen therapy for Radiation-Damaged jaws falls short in early trial

NCT ID NCT00989820

Terminated Disease control Sponsor: Radboud University Medical Center Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 34 times

Summary

This study looked at whether breathing pure oxygen in a special chamber (hyperbaric oxygen therapy) could help heal jaw damage caused by cancer radiation. The trial planned to include 20 adults with long-lasting jaw bone damage, but it was stopped early. The goal was to see if the treatment could fully heal the bone and reduce pain.

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Contacts and locations

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Locations

Erasmus University Medical Center

Rotterdam, 3015CE, Netherlands
Leiden University Medical Center

Leiden, 2333ZA, Netherlands
Maastricht Universitary Medical Centre

Maastricht, 6229HX, Netherlands
NKI/AvL

Amsterdam, 1066CX, Netherlands
Radboud University Nijmegen Medical Centre

Nijmegen, 6525GA, Netherlands
University Medical Center Groningen

Groningen, Netherlands
University Medical Center Utrecht

Utrecht, 3584CX, Netherlands
VU University Medical centre

Amsterdam, Netherlands

Conditions

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OSTEORADIONECROSIS