Oxygen chamber therapy tested for jaw bone decay after cancer radiation
NCT ID NCT00989820
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether breathing pure oxygen in a pressure chamber (hyperbaric oxygen therapy) can help heal jaw damage caused by radiation treatment for cancer. The trial planned to include 20 people with jaw bone decay, but it was stopped early. The goal was to see if the therapy could close exposed bone and reduce pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyperbaric oxygen therapy
- What this could lead to
- If effective, this could offer a way to heal jaw damage caused by radiation therapy without major surgery.
- What could go wrong
- The trial was terminated early and only enrolled 20 people, so we don't have enough data to know if it works. Hyperbaric oxygen can cause ear pain or pressure injuries in rare cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OSTEORADIONECROSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Erasmus University Medical Center
Rotterdam, 3015CE, Netherlands
-
Leiden University Medical Center
Leiden, 2333ZA, Netherlands
-
Maastricht Universitary Medical Centre
Maastricht, 6229HX, Netherlands
-
NKI/AvL
Amsterdam, 1066CX, Netherlands
-
Radboud University Nijmegen Medical Centre
Nijmegen, 6525GA, Netherlands
-
University Medical Center Groningen
Groningen, Netherlands
-
University Medical Center Utrecht
Utrecht, 3584CX, Netherlands
-
VU University Medical centre
Amsterdam, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.