Osteochondritis dissecans
MONDO:0017178A rare bone disease characterized by an acquired idiopathic necrotic lesion of subchondral bone with the formation of a sequestrum, which may detach to form loose bodies in joints. OCD mainly affects the knee, ankle and elbow joints and can lead to pain, functional limitations and secondary osteoarthritis.
Also known as: Koenig disease, Konig disease, König disease, OD, osteochondritis dissecans, osteochondritis dissecans (disease), familial osteochondritis dissecans, SSOAOD
20 clinical trials for this condition and its sub-types, 20 tagged with Osteochondritis dissecans itself.
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New hip implant aims to fix cartilage without replacement
Disease control OngoingThis early study is testing a new device called the ReNew Hip Implant in 15 people aged 14 to 64 with hip cartilage damage from conditions like osteoarthritis or hip impingement. The implant is surgically placed to repair the cartilage. Researchers are checking if it is safe and …
Sponsor: Cytex Therapeutics, Inc. • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Can a tiny metal plug fix painful ankle defects?
Disease control OngoingThis trial tests whether a small metal implant, called the Episealer Talus, can relieve pain and improve function in people with a specific type of ankle cartilage damage. The study will enroll 20 adults aged 18 to 65 who have a focal defect on the talus bone and have not improve…
Sponsor: Stefano Zaffagnini • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Can a single surgery fix ankle cartilage for a decade? a long-term study puts AMIC to the test.
Disease control OngoingThis study looks at how well a surgical technique called AMIC holds up ten years after repairing cartilage damage in the ankle. Researchers are checking whether the pain relief and function patients gained in the first few years remain stable or fade over time. About 40 people wh…
Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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3D printing and plasma team up to fix knee cartilage
Disease control OngoingThis study tests a new way to repair damaged knee cartilage using 3D printing, platelet-rich plasma, and a piece of the patient's own bone and tissue. It involves 60 adults with large cartilage injuries. The goal is to see if this approach improves knee function and helps cartila…
Sponsor: Second Affiliated Hospital of Nanchang University • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Can donor cartilage transplants stand the test of time? a lifelong registry aims to find out
Knowledge-focused By invitation onlyThis registry follows patients who receive donor cartilage or meniscus transplants for joint defects in the knee, hip, ankle, or shoulder. Researchers are collecting long-term data on pain, function, and whether the grafts need revision or fail over time. The goal is to understan…
Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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Knee injury study reveals hidden stress in young athletes
Knowledge-focused OngoingThis study looks at how a knee condition called osteochondritis dissecans (OCD) affects the mental health of young athletes aged 11 to 19. Researchers will measure stress and depression levels in 120 patients as they go through standard treatment, either surgery or non-surgical c…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Knee OCD study seeks best treatment path
Knowledge-focused OngoingThis study looks at 254 people with a knee condition where a piece of bone and cartilage starts to crack and loosen. Researchers are observing how well different standard treatments—like rest or surgery—work over two years. The goal is to learn which approach leads to better knee…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Joint Decision-Making: what do patients really want?
Knowledge-focused By invitation onlyThis study asks over 2,300 people with various joint conditions (like arthritis, fractures, and hip problems) to fill out surveys about their treatment preferences. Researchers want to learn how factors like pain, recovery time, cost, and surgery versus non-surgery affect patient…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Ankle cartilage surgery may improve walking, new study suggests
Knowledge-focused By invitation onlyThis study looks at how people walk before and after a type of ankle surgery called arthroscopic microfracture with a biologic scaffold. The surgery is used to repair damaged cartilage in the ankle joint. Researchers will measure foot pressure and walking patterns in 60 patients …
Sponsor: Gazi University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:59 UTC