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3D printing and plasma team up to fix knee cartilage

NCT ID NCT07312175

Disease control Sponsor: Second Affiliated Hospital of Nanchang University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new way to repair damaged knee cartilage using 3D printing, platelet-rich plasma, and a piece of the patient's own bone and tissue. It involves 60 adults with large cartilage injuries. The goal is to see if this approach improves knee function and helps cartilage heal better than standard methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-65 years; 2. Body Mass Index (BMI) 18-30 kg/m²; 3. Imaging-confirmed knee cartilage damage \>2 cm² with International Cartilage Repair Society (ICRS) grade 4; 4. No significant lower limb alignment abnormalities; 5. No prior local drug injections in the knee joint within the past year. Exclusion Criteria: 1. Significant osteoporosis; 2. Individuals with immature bones; 3. Those with poor mechanical alignment; 4. Presence of meniscus injury, cruciate ligament or collateral ligament rupture, or incomplete healing following surgery for any of these conditions; 5. Severe knee joint effusion; 6. Use of corticosteroids or immunosuppressive agents; 7. Poor general health, alcoholism, or substance abuse; 8. Previous treatment with autologous blood products or stem cell preparations.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteochondritis dissecans

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteo arthritis Osteochondral lesions of knee

Contacts and locations

Locations

  • 330006

    Nanchang, Jiangxi, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.