Optic choroid disorder
MONDO:0001898A disease involving the optic choroid.
Also known as: choroid disorder, disease of optic choroid, disease or disorder of optic choroid, disorder of optic choroid, optic choroid disease, optic choroid disease or disorder, choroid disease
26 clinical trials for this condition and its sub-types, 6 tagged with Optic choroid disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Optic choroid disorder
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Choroid neoplasm 0 trials · 10 incl. sub-types
2 sub-types
- Choroid cancer 0 trials · 10 incl. sub-types Sub-types →
- Benign neoplasm of choroid 0 trials Sub-types →
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Choroideremia 6 trials
2 sub-types
- Choroideremia hypopituitarism 0 trials
- Total central choroidal atrophy 0 trials
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5 sub-types
- Choroidal dystrophy, central areolar 2 0 trials
- Choroidal dystrophy, central areolar, 1 0 trials
- Choroidal dystrophy, central areolar, 3 0 trials
- Partial central choroid dystrophy 0 trials
- Total central choroidal atrophy 0 trials
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Choroiditis 0 trials · 1 incl. sub-types
4 sub-types
- Serpiginous choroiditis 1 trial
- Infectious posterior uveitis 0 trials
- Multifocal choroiditis 0 trials Sub-types →
- Paraneoplastic uveitis 0 trials
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Choroidal sclerosis 0 trials
4 sub-types
- Angioid streaks of choroid 0 trials
- Diffuse secondary choroid atrophy 0 trials
- Hereditary choroidal atrophy 0 trials Sub-types →
- Senile atrophy of choroid 0 trials
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1 sub-type
- Basal laminar drusen 0 trials
Most studied deeper sub-types
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New eye injection could spare sight in melanoma patients
Disease control OngoingThis Phase 3 trial tests a new drug called belzupacap sarotalocan (AU-011) for people with small choroidal melanoma or suspicious spots in the eye. The drug is injected into the eye and activated by a laser to target cancer cells. The study compares it to a sham (fake) procedure …
Phase 3 • Sponsor: Aura Biosciences • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Liver-Directed chemo shows promise for eye cancer metastases
Disease control OngoingThis phase 2 trial tests a procedure called transarterial chemoembolization (TACE) for people with uveal melanoma that has spread to the liver. Doctors inject a chemotherapy drug (carmustine) mixed with an oily contrast agent (Lipiodol) directly into the liver's blood supply, the…
Phase 2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Gene therapy injection aims to restore sight in rare eye diseases
Disease control OngoingThis early-phase trial tests a single injection of a gene therapy called RTx-015 in 10 adults with retinitis pigmentosa or choroideremia, two inherited conditions that cause vision loss. The therapy delivers a gene that makes retinal cells produce a light-sensitive protein, poten…
Phase 1 • Sponsor: Ray Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New combo therapy aims to shrink eye tumors before radiation
Disease control By invitation onlyThis early-phase trial tests whether injecting the chemotherapy drug melphalan directly into the eye's blood vessels can shrink large uveal melanomas (eye cancers) enough to then treat them with radiation. Ten adults with tumors at least 8 mm thick will receive the chemo injectio…
Phase 1/2 • Sponsor: Hospital das Clínicas de Ribeirão Preto • Aim: Disease control
Last updated Jun 26, 2026 17:03 UTC
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Newborn screening study aims to catch rare diseases at birth
Diagnosis OngoingThis study offers voluntary screening for newborns in North Carolina to detect a wide range of rare health conditions early. Using a small blood sample already collected at birth, the program tests for dozens of disorders, including spinal muscular atrophy, cystic fibrosis, and m…
Sponsor: RTI International • Aim: Diagnosis
Last updated Jul 03, 2026 00:00 UTC
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Researchers track Long-Term safety of experimental eye cancer treatment
Knowledge-focused By invitation onlyThis study is a long-term follow-up for 100 people who completed a previous trial of bel-sar, an experimental treatment for early choroidal melanoma (a type of eye cancer). Participants will not receive any new treatment but will be monitored for about 5 more years to check for s…
Sponsor: Aura Biosciences • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Scientists track rare eye disease to uncover clues for future treatments
Knowledge-focused OngoingThis study follows 46 people with gyrate atrophy, a rare genetic condition that causes vision loss, over 4 years. Researchers measure ornithine levels in the blood and track changes in the retina using eye scans and photos. The goal is to learn how the disease progresses under st…
Sponsor: Jaeb Center for Health Research • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Researchers track Long-Term safety of experimental eye cancer drug
Knowledge-focused OngoingThis registry follows 63 patients with choroidal melanoma or early eye lesions who were treated with the experimental drug bel-sar in earlier studies. The goal is to monitor long-term safety, side effects, and any spread of the disease over time. Participants are not receiving ne…
Sponsor: Aura Biosciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC