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New study tracks rare eye disease to unlock its secrets

NCT ID NCT05312736

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 22 times

Summary

This study follows 46 people with gyrate atrophy, a rare genetic condition that causes vision loss, over 4 years. Researchers measure ornithine levels in the blood and track changes in the retina using eye scans and photos. The goal is to learn how the disease progresses under standard dietary care, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, INSERM-DGOS CIC1423

    Paris, 75012, France

  • Harvard Univ., Massachusetts Eye and Ear Infirmary

    Boston, Massachusetts, 02114, United States

  • Helsinki University Hospital

    Helsinki, 00280, Finland

  • INRET Clínica e Centro de Pesquisa

    Belo Horizonte, Minas Gerais, 30150-270, Brazil

  • Johns Hopkins University, Wilmer Eye Institute

    Baltimore, Maryland, 21287, United States

  • Moorfields Eye Hospital

    London, UK EC1V 2PD, United Kingdom

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Toronto, Hospital for Sick Children

    Toronto, Ontario, M5G0A4, Canada

  • University of Tuebingen, Centre for Ophthalmology

    Tübingen, 72076, Germany

  • Vista Vision Eye Clinic

    Brescia, 25123, Italy

Conditions

Explore the condition pages connected to this study.