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Nodular goiter
MONDO:0006869Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.
Also known as: goiter, nodular, nodular goiter, nodular goiter (disease), nodular goitre (disease), nodular goitre NOS
43 clinical trials for this condition and its sub-types, 36 tagged with Nodular goiter itself.
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Sub-types of Nodular goiter
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Multinodular goiter 10 trials
3 sub-types
- Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors 1 trial
- Goiter, multinodular 2 0 trials
- Goiter, multinodular 3 0 trials
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AI boosts thyroid nodule diagnosis, may cut unnecessary biopsies
Diagnosis CompletedThis study tested whether artificial intelligence (AI) can improve the accuracy of contrast-enhanced ultrasound for diagnosing thyroid nodules. Nearly 2,000 participants had both an ultrasound and a biopsy to confirm their diagnosis. Researchers compared how well doctors could id…
Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Thinner needle for thyroid biopsy may reduce pain without sacrificing accuracy
Symptom relief CompletedThis study compares two needle sizes (21-gauge vs 27-gauge) used for ultrasound-guided fine needle biopsy of thyroid nodules. The goal is to see which size causes less pain and discomfort during the procedure while still collecting enough cells for diagnosis. Adults with thyroid …
Sponsor: Izmir Ataturk Training and Research Hospital • Aim: Symptom relief
Last updated Aug 01, 2026 00:00 UTC
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No-Drain thyroid surgery shows promise for benign nodules
Symptom relief CompletedThis study looked at whether removing benign thyroid nodules without placing a surgical drain is safe and effective. Eighty adults having thyroid surgery were randomly assigned to either the standard drain or a no-drain, sutureless technique. The goal was to see if the no-drain a…
Sponsor: Minia University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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New study aims to decode cancer risk in treated thyroid nodules
Knowledge-focused CompletedThis study follows 180 people who had a benign thyroid nodule treated with radiofrequency heat ablation three years ago. Researchers will use ultrasound and a fine-needle biopsy to see how the nodule looks and whether any cells have changed. The goal is to create a better way to …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Skipping thyroid ultrasound after PET may be safe, study suggests
Knowledge-focused CompletedThis study examines whether patients who have a thyroid nodule found on a PET scan can safely skip a follow-up ultrasound without affecting their survival. Researchers will compare death rates over 7 years between those who had an ultrasound within 3 months and those who did not.…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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Can a simple conversation tool reduce unnecessary thyroid biopsies?
Knowledge-focused CompletedThis study tested a digital conversation aid to help patients and doctors make shared decisions about thyroid biopsy. Researchers enrolled 107 adults with thyroid nodules to see if using the tool during clinic visits was practical. The goal was to gather information for planning …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC