Monomelic amyotrophy
MONDO:0011224Monomelic amyotrophy (MA) is a rare benign lower motor neuron disorder characterized by muscular weakness and wasting in the distal upper extremities during adolescence followed by a spontaneous halt in progression and a stabilization of symptoms.
Also known as: Hirayama disease, JMADUE, benign focal amyotrophy, juvenile muscular atrophy of distal upper extremity, juvenile muscular atrophy of the distal upper limb, amyotrophy, monomelic, spinal muscular atrophy juvenile nonprogressive, spinal muscular atrophy, juvenile, nonprogressive
9 clinical trials for this condition and its sub-types, 0 tagged with Monomelic amyotrophy itself.
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Browse by category →Sub-types of Monomelic amyotrophy
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O'Sullivan-McLeod syndrome 0 trials
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Mind-Controlled tablets: brain implant trial aims to give voice to the paralyzed
Disease control Recruiting nowThis early-stage trial tests a brain-computer interface called BrainGate for people with paralysis from conditions like ALS or spinal cord injury. A small sensor is placed in the brain to interpret movement-related signals, allowing users to control a tablet computer just by thin…
Sponsor: Leigh R. Hochberg, MD, PhD. • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Smart trial takes on MND: could existing drugs slow the disease?
Disease control Recruiting nowThis study tests several already-approved drugs to see if they can slow down motor neuron disease (MND) and help people live longer. About 1150 adults with MND will be randomly assigned to receive one of the study drugs or a placebo. The trial uses a flexible design, allowing ine…
Phase 2/3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Can brain zaps and video games slow ALS?
Disease control Recruiting nowThis study tests a new approach for people with motor neuron disease (ALS) that combines personalized brain stimulation with mixed reality exercise games. The goal is to slow disease progression and improve quality of life. One hundred adults with mild to moderate ALS will be ran…
Sponsor: Chulalongkorn University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Ultra-Strong MRI scans could spot ALS earlier
Diagnosis Recruiting nowMotor neuron disease (MND), including ALS, is hard to diagnose and often takes years to confirm. This pilot study uses a powerful 7 tesla MRI scanner to look for detailed brain features, called imaging biomarkers, that are specific to MND and its subtypes. Researchers will scan 3…
Sponsor: NHS Greater Glasgow and Clyde • Aim: Diagnosis
Last updated Sep 16, 2026 00:00 UTC
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Your phone could detect dementia: new app listens for clues
Diagnosis Recruiting nowThis study is testing a smartphone app that records and analyzes speech to help diagnose and monitor neurodegenerative conditions like dementia, Parkinson's disease, multiple sclerosis, and motor neuron disease. Researchers will compare speech patterns from 150 people with these …
Sponsor: University of Edinburgh • Aim: Diagnosis
Last updated Sep 12, 2026 00:00 UTC
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Mind-Controlled devices: new study aims to help paralysis patients
Knowledge-focused Recruiting nowThis study explores whether a non-invasive brain-computer interface (BCI) can help people with motor disorders, such as spinal cord injury or stroke, control assistive devices using their thoughts. Researchers will record brain signals with EEG and use machine learning to interpr…
Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC