Microinvasive gastric cancer

This study tests a new surgery for early gastric cancer that uses two scopes (a laparoscope and an endoscope) to guide the removal of sentinel lymph nodes. The goal is to see if this approach is safe and effective. The study involves 36 people with early-stage stomach cancer.

This study tests a new surgical approach for early gastric cancer that uses a fluorescent dye to help surgeons see and remove only the cancerous lymph nodes, sparing healthy tissue. About 312 patients will be randomly assigned to either this new technique or standard surgery. The…

This study is testing an artificial intelligence (AI) model designed to help doctors detect early gastric (stomach) cancer during endoscopy. The AI combines images from standard and enhanced endoscopy with patient data to improve accuracy and explain its reasoning. Researchers wi…

This study tests a special fluorescent dye that attaches to cancer cells to help doctors see if lymph nodes contain cancer during surgery for early gastric cancer. About 47 people with early gastric cancer will have their removed lymph nodes examined with this probe. The goal is …

This study tests whether using a special imaging technique called Red Dichromatic Imaging (RDI) throughout the entire ESD procedure can reduce serious complications like bleeding and perforation, and shorten surgery time. About 640 adults with early stomach cancer or precancerous…

This study tests whether a smartphone app that lets cancer patients report their symptoms, combined with regular calls from a specially trained nurse, can help them better manage chemotherapy side effects and improve their quality of life. The study includes 414 adults with early…

This study will examine 4,000 adults aged 40 and older in India using high-definition endoscopy to find early stomach cancer and precancerous changes. Participants are people already scheduled for an upper GI endoscopy due to digestive symptoms. The goal is to learn how common th…

This study looks back at the medical records of about 5,000 people in China treated for early gastric cancer. It compares different treatment approaches—such as endoscopic removal, laparoscopic surgery, open surgery, or a combination—to see how they affect long-term survival and …

This study looks at whether the presence and distribution of H. pylori bacteria in the stomach, along with tissue features of early gastric cancer, can help predict how the cancer will behave and what the long-term outlook may be. Researchers will analyze data from about 1,500 pe…

This study is gathering images from special cameras and CT scans, along with lab results, to create a database for early upper gastrointestinal cancers and precancerous conditions. About 500 adults who need certain procedures will take part. The goal is to help doctors better rec…

This study tests a new AI system (AI-ENDO) that helps doctors perform a type of keyhole surgery called endoscopic submucosal dissection (ESD) for early-stage cancers in the food pipe, stomach, or bowel. The AI works in the background at first, then provides real-time guidance on …

This study is building a registry of 3,200 people with early changes in the stomach lining that can lead to gastric cancer. Researchers will collect information on lifestyle, diet, and other risk factors through questionnaires. The goal is to better understand why some people dev…

This study looks at how the H. pylori bacterium is distributed in different stages of stomach inflammation and early gastric cancer. Researchers will examine tissue samples from 231 people using a special staining technique to see where and how much bacteria are present. The goal…

This study is collecting tissue and blood samples from 1,730 people with early gastric cancer or precancerous stomach growths. Researchers will analyze the genetic profiles of these samples to find markers that could help diagnose these conditions early and predict if the cancer …