Stomach bug patterns could reveal cancer risk early
NCT ID NCT07253948
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the H. pylori bacterium is distributed in different stages of stomach inflammation and early gastric cancer. Researchers will examine tissue samples from 231 people using a special staining technique to see where and how much bacteria are present. The goal is to find patterns that could help doctors screen for early stomach cancer more effectively.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify patterns of H. pylori infection that signal a higher risk of early gastric cancer, improving screening strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove that changing H. pylori levels prevents cancer, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 231 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Cases that underwent gastric H. pylori immunohistochemical staining at our center from March 1, 2023, to August 15, 2025.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age 18-80 years * received H. pylori immunohistochemical testing at our center and tested positive. Exclusion Criteria: * biopsies not collected from both the greater and lesser curvatures of the gastric antrum and body * history of stomach surgery * suspected autoimmune gastritis under endoscopy * liver cirrhosis * severe comorbidities such as advanced cancer or renal failure * advanced gastric cancer or gastric lymphoma
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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the First Hospital of Jilin University
RECRUITINGChangchun, Jilin, 130021, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Which treatment for early stomach cancer offers the best Long-Term survival?
- Stomach bug clues: can infection patterns forecast early cancer behavior?
- Shorter h. pylori treatment shows promise in new trial
- Fluorescent dye guides Stomach-Sparing surgery for early cancer
- New Dual-Scope surgery shows promise for early stomach cancer