Methamphetamine dependence

This study tests whether offering rewards (contingency management) can help people who use methamphetamine reduce their use after a traumatic injury. Twenty adults admitted to the hospital with a positive meth test will receive urine tests and rewards for negative results, starti…

This study tests whether tirzepatide, a drug approved for weight management, can help people who are obese and have a moderate to severe stimulant use disorder (like methamphetamine or cocaine). Participants receive weekly injections for 20 weeks, along with counseling and brain …

This study tests whether intravenous ketamine can help people with moderate to severe methamphetamine use disorder reduce their drug use. Over 12 weeks, 120 adults will receive either ketamine or a mild sedative (midazolam) in six sessions. The main goal is to see if more partici…

This Phase 3 trial tests whether a combination of extended-release naltrexone (Vivitrol) and bupropion XL (Wellbutrin) can help people with moderate to severe methamphetamine use disorder reduce their drug use. About 360 participants will receive either the active drugs or placeb…

This pilot study tests a web-based program called LDART for adults with stimulant use disorder (cocaine or methamphetamine). The program includes daily goal setting, motivational messages from people in recovery, and links to support groups. Researchers want to see if it's feasib…

This early-stage trial tests whether psilocybin, the active ingredient in magic mushrooms, combined with psychotherapy can help veterans with moderate to severe methamphetamine use disorder. Thirty participants will receive either psilocybin-enhanced therapy or standard treatment…

This study tests whether a short, group-based stress management training program can help caregivers of people with methamphetamine ("ice") addiction and psychosis. Caregivers often face high levels of emotional and physical stress, which can lead to burnout. The program teaches …

This study aimed to see if a non-invasive brain stimulation technique called TMS could help people with methamphetamine use disorder control their cravings. Researchers planned to recruit 40 adults living in a residential treatment program and give some real stimulation and other…

This study looks at how people's bodies react to stress in a pretend emergency room. Researchers will have 30 adults (20 who use meth and 10 healthy volunteers) do public speaking and math tasks while measuring stress hormones, heart rate, and blood pressure. The goal is to see i…