Maternally-inherited diabetes and deafness

This study tested a new drug called OMT-28 in 28 people with primary mitochondrial disease, a condition that affects how cells produce energy. Participants took the drug once daily for 6 months, and researchers measured safety, blood markers of inflammation, and symptoms like fat…

This study looked at the safety of vatiquinone in 101 people with inherited mitochondrial disease who had already taken the drug in a previous study or treatment plan. The goal was to track any side effects until the drug became commercially available or the program ended. Partic…

Researchers are evaluating four blood glucose meters and four HbA1c point-of-care devices to see how accurately they measure blood sugar and long-term glucose control compared with standard lab methods. The study includes people with diabetes, both adults and teenagers, some of w…

This trial tests whether a quick cold spray on the skin before a subcutaneous insulin injection can reduce pain compared to a placebo spray. Adults in the emergency department who need at least two insulin injections receive both sprays in random order, rating their pain after ea…

This study tested custom-made insoles for people with diabetic foot to see if they improve balance and walking. Twenty-five participants aged 40 to 65 with early-stage diabetic foot issues were included. The insoles were designed using pressure measurements to offload high-pressu…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This observational study looks at records from Israel's National Insurance Institute to understand how often diabetes is linked to permanent disability. It will compare disability rates and severity across different regions and over time, from 2020 to 2025. No treatments or tests…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This study tested whether taking acetaminophen (like Tylenol) interferes with a new continuous glucose monitor called Biolinq. Thirty-one adults with diabetes wore the Biolinq sensor and a standard CGM for three days. On day three, they took acetaminophen and researchers compared…

This completed study looked at how diet and exercise change blood sugar levels in 61 adults with diabetes. Researchers used advanced tests (genomics, proteomics, etc.) to understand the body's complex response. The goal is to build a tool that helps doctors personalize diabetes c…