Lymphatic malformation

MONDO:0019313

Primary lymphedema is caused by anatomic or functional defects in the lymphatic system, resulting in chronic swelling of body parts and lymphatic-system malformation.

Also known as: hereditary lymphedema, lymphedema, hereditary

55 clinical trials for this condition and its sub-types, 17 tagged with Lymphatic malformation itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disease (18187) ↑ Vascular disorder (10696) ↑ Primary lymphedema (65)

Sub-types of Lymphatic malformation

Noonan syndrome 21 trials · 24 incl. sub-types
14 sub-types
- Noonan syndrome 3 2 trials
- Noonan syndrome 5 1 trial
- Noonan syndrome 1 0 trials
- Noonan syndrome 10 0 trials
- Noonan syndrome 11 0 trials
- Noonan syndrome 13 0 trials
- Noonan syndrome 14 0 trials
- Noonan syndrome 2 0 trials
- Noonan syndrome 4 0 trials
- Noonan syndrome 6 0 trials
- Noonan syndrome 7 0 trials
- Noonan syndrome 8 0 trials
- Noonan syndrome 9 0 trials
- Noonan syndrome 12 0 trials
Lymphatic malformation 5 8 trials
Anhidrotic ectodermal dysplasia-immunodeficiency-osteopetrosis-lymphedema syndrome 4 trials
Lymphatic malformation 12 2 trials
MPI-congenital disorder of glycosylation 1 trial
Deafness-lymphedema-leukemia syndrome 1 trial
Dahlberg-Borer-Newcomer syndrome 0 trials
Hennekam syndrome 0 trials
3 sub-types
- Hennekam lymphangiectasia-lymphedema syndrome 1 0 trials
- Hennekam lymphangiectasia-lymphedema syndrome 2 0 trials
- Hennekam lymphangiectasia-lymphedema syndrome 3 0 trials
Norman-Roberts syndrome 0 trials
Campomelia, Cumming type 0 trials
Congenital primary lymphedema of Gordon 0 trials
Hypotrichosis-lymphedema-telangiectasia syndrome 0 trials
Hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 0 trials
Lymphatic malformation 1 0 trials
Lymphatic malformation 10 0 trials
Lymphatic malformation 11 0 trials
Lymphatic malformation 13 0 trials
Lymphatic malformation 14 0 trials
Lymphatic malformation 2 0 trials
Lymphatic malformation 3 0 trials
Lymphatic malformation 4 0 trials
Lymphatic malformation 6 0 trials
Lymphatic malformation 7 0 trials
Lymphatic malformation 8 0 trials
Lymphatic malformation 9 0 trials
Lymphedema-distichiasis syndrome 0 trials
Microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability 0 trials
Yellow nail syndrome 0 trials

Including sub-types (55) Tagged with Lymphatic malformation (17)

Trials to join now! 26 Not yet recruiting 5 Not yet finished but already full! 8 Completed 15 Terminated 1

New cancer pill shows early promise, but trial halted

Disease control Stopped early

This early-stage trial tested an oral drug called TNO155, alone or with another drug (nazartinib), in 227 adults with advanced solid tumors like lung cancer, melanoma, and head/neck cancer. The main goal was to check safety and find the right dose. The study was terminated early,…

Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control

Last updated Jul 11, 2026 00:00 UTC

Lymphatic malformation

Where it sits in the disease tree

New cancer pill shows early promise, but trial halted